نتایج جستجو برای: felodipine

تعداد نتایج: 381  

Journal: :International journal of clinical and experimental medicine 2015
Ya-Feng Yu Wen-Ying Wu Gen-Sheng Xiao Jian Shi Hong-Yang Ling

To explore the expression levels of T-type calcium channel receptors in spiral ganglion neurons of C57BL/6J mice and the effect of T-type calcium channel blockers on the spiral ganglion neurons of 42-44-W C57BL/6J mice. We first quantified the subunits of T-type calcium channel blockers in the spiral ganglion neurons of C57BL/6J mice in three groups (6-8 W, 24-26 W, 42-44 W) according to age vi...

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Journal: :Circulation research 1984
M J Mulvany C Aalkjaer T T Petersen

We have investigated effects of altered extracellular sodium, intracellular sodium concentration, and membrane potential on the contractile responses of rat isolated mesenteric small arteries (internal diameter ca. 200 microns), when mounted as ring preparations on an isometric myograph. To avoid possible neural effects, all vessels were denervated in vitro using 6-hydroxydopamine. In unstimula...

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Journal: :The Journal of pharmacology and experimental therapeutics 2008
Ivan Zahradník Igor Minarovic Alexandra Zahradníková

Antidepressants inhibit many membrane receptors and ionic channels, including the L-type calcium channel. Here, we investigated the inhibition of calcium current (I(Ca)) by antidepressants in enzymatically isolated rat ventricular myocytes using whole-cell patch clamp. The molecular mechanism of inhibition was studied by comparing the voltage and state dependence of antidepressant inhibition of...

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Journal: :RSC Advances 2020

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Journal: :International Journal of Pharmacology 2015

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Journal: :Journal of Pharmaceutical Sciences 2018

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Journal: :The Journal of Heart and Lung Transplantation 2020

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Journal: :Japanese Journal of Pharmacology 1989

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Journal: :Clinical Pharmacology & Therapeutics 2004

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Journal: :American journal of hypertension 1997
J Mayet N Chapman M Shahi N R Poulter D A Cunningham S Dave J Kooner P S Sever R A Foale S A Thom

To examine the effects of antihypertensive therapy causing regression of left ventricular hypertrophy on cardiac arrhythmias, 26 hypertensive subjects were treated with ramipril with felodipine if required, and followed for 6 months after blood pressure control. Compared with baseline, left ventricular mass index (LVMI) was significantly reduced both at blood pressure control and after a furthe...

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