Atomic force microscopy (AFM) has been employed to investigate characteristics of tracks of heavy charged particles in solid state nuclear track detectors (SSNTDs). In the present work, we have performed simulations of the track structures revealed by AFM based only on geometrical considerations of the tracks and two types of probes (the ultralever and the ultrahigh aspect ration probe). The pu...

     The purpose of the present study was to explore the passive and electrically assisted transdermal transport of Granisetron hydrochloride (GRA) in solution and gel formulation through iontophoresis and also the feasibility of delivering therapeutic amounts of drug for the treatment of chemotherapy-induced nausea and vomiting. In this study, iontophoretic permeation of GRA through guinea pig...

Renal apparent diffusion coefficients (ADCs) were anisotropic within and significantly different between cortex and medulla using a relatively motion-insensitive one-dimensional technique in 20 volunteers. ADC values ranged from 1.79 +/- .39 to 2.95 +/- .58 (x 10(-3)mm2/sec), relatively high but similar to other reports. Further investigation may help clarify this data, and determine whether th...

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Pilot/feasibility studies can be an essential part of trial preparation, particularly in planning complex interventions. However, recent research indicates that these studies suffer from publication bias and a lack of clarity in the objectives and methodological focus. Misunderstandings about the purpose of pilot/feasibility studies mean that opportunities to answer the important research quest...

A preliminary investigation was initiated in 1984 to determine the feasibility of an urban rabies control strategy which involved capturing, vaccinating and releasing skunks and raccoons in metropolitan Toronto, Ontario. Results indicate urban skunks and raccoons are utilizing extremely small home ranges and their movements are not extensive. Trapping data suggested a large proportion of the po...