Here, core-shell structured polydopamine-coated Fe3O4 nanoparticles were constructed to immobilize thermostable lipase QLM from Alcaligenes sp. Systematical characterization indicated that lipase QLM was successfully immobilized on the surface of nanoparticles with an enzyme loading of 21.4 ± 1.47 mg/g immobilized enzyme. Then, the immobilized enzyme was demonstrated to possess favorable cataly...

BACKGROUND Multifunctional magnetic nanoparticles are important class of materials in the field of nanobiotechnology, as it is an emerging area of research for material science and molecular biology researchers. One of the various methods to obtain multifunctional nanomaterials, molecular functionalization by attaching organic functional groups to nanomagnetic materials is an important techniqu...

The elimination of b-agonist has attracted considerable interest due to its harmfulness to human health when it existed in pork. Here, a strategy based on immuno-magnetic nanoparticles has been successfully developed for the selective and successive magnetic separation of two kinds of b-agonists, clenbuterol (CL) and salbutamol (SAL). The calibration curve of competitive immunoassay was determi...

Hydrazide chemistry is a powerful technique in glycopeptides enrichment. However, the low density of the monolayer hydrazine groups on the conventional hydrazine-functionalized magnetic nanoparticles limits the efficiency of glycopeptides enrichment. Herein, a novel magnetic nanoparticle grafted with poly(glycidyl methacrylate) (GMA) brushes was fabricated via reversible addition-fragmentation ...

BACKGROUND Iron oxide nanoparticles are of considerable interest because of their use in magnetic recording tape, ferrofluid, magnetic resonance imaging, drug delivery, and treatment of cancer. The specific morphology of nanoparticles confers an ability to load, carry, and release different types of drugs. METHODS AND RESULTS We synthesized superparamagnetic nanoparticles containing pure iron...

This study aims to evaluate the multidrug resistance (MDR) reversal activity by magnetic nanoparticles of Fe3O4 (MNPs-Fe3O4) and 5-bromotetrandrine (BrTet) MDR cell line K562/A02 solitarily or symphysially. The proliferation of K562 and K562/A02 cells and the cytotoxicity on peripheral blood mononuclear cells (PMBCs) were evaluated by MTT assay. Cellular accumulation of daunorubicin (DNR) was a...

A carbon-encapsulated Fe3O4 nanocomposite was prepared by a simple one-step pyrolysis of iron pentacarbonyl without using any templates, solvents or surfactants. The structure and morphology of the nanocomposite was investigated by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, Brunauer-Emmett-Teller analysis and Raman spectroscopy. Fe3O4 nanoparticles are di...

Nearly monodispersed yolk-type Au@Fe3O4@C nanospheres with hollow cores of 50 nm in diameter were prepared through coating Au@SiO2 nanoparticles with Fe3O4@C double layers, followed by dissolving SiO2. The cytotoxicity of the nanospheres was evaluated by MTT assay, demonstrating a high biocompatibility. The yolk-type nanospheres show a high DOX loading content of 1237 mg g(-1). The coexistence ...

this study investigated the applicability of polyethylene glycol (peg-4000) coated fe3o4 magnetic nanoparticles for the selective removal of toxic pb (ii) ion from wastewater. the fe3o4 magnetic nanoparticles of 24 nm were synthesized using a coprecipitation method and characterized by scanning electron microscopy (sem), vibratingsample magnetometer (vsm), and x-ray diffraction (xrd). sem image...

In this paper, Fe3O4-chitosan nanoparticles were prepared by the immobilization of chitosan on the surface of Fe3O4 nanoparticles. Then, the 5-substituted hydantoins were synthesized from the condensation of aldehyde derivatives, ammonium carbonate and zinc cyanide as a well-known cyanating agent by the magnetic Fe3O4-chitosan nanoparticles under neat conditions. Fe3O4-Chitosan nanocatalyst as ...