Wnt-5a is a representative ligand that activates a beta-catenin-independent pathway in Wnt signalling. In the present paper, the roles of the post-translational modifications in the actions of Wnt-5a were investigated. We found that Wnt-5a is modified with palmitate at Cys104 and glycans at Asn114, Asn120, Asn311 and Asn325. The palmitoylation was not essential for the secretion of Wnt-5a, but ...

According to the results of EPR spectroscopy associates of the complex molecules [Cu(ox)2] are formed on the external surface of the carrier by the reaction of 8-quinolinol (Hox) with highly mobile Cu(II) aqua complexes exchanged in the supercavities of fully hydrated Y zeolite. The reaction of Hox with Cu(II) exchanged zeolite Y, dehydrated in vacuo at 20 °C, 200 °C, and 400 °C, leads to segre...

Synthesis of nanoparticles of TiO2, Pt, CdS, and their binary and ternary combinations were made on zeolite Y starting frommolecular precursors that are ion exchanged into the zeolite.Nanoclusters ofTiO2 in the anatase formwere formed from titanyl ions at low loadings of Ti (1 per 2.5 supercages). CdS (hexagonal form) andmetallic Pt were formed fromCd2þ and Pt(NH3)4 2þ ion exchanged into the ze...

Two flame retarded plastics have been pyrolysed in the presence of two Zeolite catalysts to remove the organobromine compounds from the derived pyrolysis oil. The flame retarded plastics were, acrylonitrile – butadiene – styrene (ABS) that was flame retarded with tetrabromobisphenol A and high-impact-polystyrene (HIPS) that was flame retarded with decabromodiphenyl ether. The two catalysts inve...

Measurement by impedance spectroscopy of the changes in intrazeolitic cation motion of pressed pellets of zeolite particles upon adsorption of dimethylmethylphosphonate (DMMP) provides a strategy for sensing DMMP, a commonly used simulant for highly toxic organophosphate nerve agents. In this work, two strategies for improving the impedance spectroscopy based sensing of DMMP on zeolites were in...

A number of potentiometric biosensors based on coimmobilization of enzymes with different types of zeolite on pH-ion-sensitive field-effect transistor (ISFET) have been developed. Their working characteristics have been determined and compared. It was shown that clinoptilolite and zeolite Beta polymorph A (BEA) are more promising for creating biosensors than zeolite A. Changing the concentratio...

In order to investigate cecal coccidiosis in broilers fed zeolite mixtures, two experiments were performed. The first was carried out in vitro, where the concentration of anticoccidial medicine not adsorbed by zeolites was determined by a spectrophotometric method. In the second experiment 100 one-day old broilers were divided into two groups that were fed with mixed feed containing the anticoc...

The increasing requirements for the environmental protection have resulted in the search for more effective, inexpensive and ecologically safe solutions. Zeolite is one of the alternatives, which due to their peculiar structure are widely used for various environmental processes. The demand for an easily accessible and inexpensive source of zeolite has raised interest in synthesis of these mine...

WNT-5A, a key player in embryonic development and post-natal homeostasis, has been associated with a myriad of pathological conditions including malignant, fibroproliferative and inflammatory disorders. Previously, we have identified WNT-5A as a transcriptional target of TGF-β in airway smooth muscle cells and demonstrated its function as a mediator of airway remodeling. Here, we investigated t...