The identification of potential new anti-tubercular chemotherapeutics is paramount due to the recent emergence of extensively drug-resistant strains of Mycobacterium tuberculosis (XDR-TB). Libraries of NAS-21 and NAS-91 analogues were synthesized and evaluated for their whole-cell activity against Mycobacterium bovis BCG. NAS-21 analogues 1 and 2 demonstrated enhanced whole-cell activity in com...

background & aim: purslane (portulaca oleracea l.), belongs to the portulacaceace family, grows in many parts of iran. results of previous studies were indicated purslane is a rich source of essential fatty acids of omega-3 and omega-6.  portulaca oleracea is a widespread weed, being the eighth common plants of the world. the aim of current study was to compare the essential fatty acids com...

Background & Aim: Purslane (Portulaca oleracea L.), belongs to the Portulacaceace family, grows in many parts of Iran. Results of previous studies were indicated purslane is a rich source of essential fatty acids of omega-3 and omega-6.  Portulaca oleracea is a widespread weed, being the eighth common plants of the world. The Aim of current study was to compare the essential f...

Despite their important role in tissues, fluids and foods, the analysis of non-esterified fatty acids (NEFA) as methyl esters (NEFAME) is performed using expensive, cumbersome and time-consuming procedures that needs of isolation, fractionation and derivatization steps. However, Yi et al. [1] proposed a promising in situ, single-step procedure to analyze esterified fatty acids (EFA) and NEFA fr...

The core objective of this study was to investigate the physicochemical characteristics and fatty acid composition oils sunflower, olive, virgin coconut ginger oils, as well separation their unsaturated acids. data indicated a significant variation in properties (acid, saponification, ester, iodine values) among oils. Transesterification process carried out at molar ratio 1:7:0.1 oil: methanol:...

Due to the concern on the availability of recoverable fossil fuel reserves and the environmental problems caused by the use those fossil fuels, considerable attention has been given to biodiesel production as an alternative to petrodiesel. However, as the biodiesel is produced from vegetable oils and animal fats, there are concerns that biodiesel feedstock may compete with food supply in the lo...

Abstract Considering the virtue of environment, usage biofuel blended fossil fuels for transportation has speeded across globe. The quality biodiesel plays an important role in efficiency a diesel engine. by transesterification method produces crude biodiesel. contains impurities like glycerol, alcohol, catalyst, and water molecules that are suspended Fatty Acid Methyl Ester (FAME) molecule. Th...

A simplified protocol to obtain fatty acid methyl esters (FAME) directly from fresh tissue, oils, or feedstuffs, without prior organic solvent extraction, is presented. With this protocol, FAME synthesis is conducted in the presence of up to 33% water. Wet tissues, or other samples, are permeabilized and hydrolyzed for 1.5 h at 55 degrees C in 1 N KOH in MeOH containing C13:0 as the internal st...

Mycolic acids were detected in both reference strains and clinical isolates of mycobacteria using gas chromatography of fatty acid methyl esters prepared by acid methanolysis. The methyl esters were extracted with hexane, concentrated, and analyzed with a gas chromatograph by using two different injector temperatures. When the samples were analyzed at high injector temperatures of 300 to 350 de...