Current presentations of the anti-HIV drugs lopinavir and ritonavir make appropriate dosing for children difficult. We conducted a feasibility study to develop a formulation for these drugs with child-safe excipients in a flexible dosage form for children across the pediatric age spectrum. The freeze-drying in blister approach was used to produce fast-dissolving tablets (FDTs), as these can be ...

Fast dissolving tablets are solid unit dosage forms that dissolve or disintegrate quickly in the mouth without using water. To provide this type of character a form, different excipients required. Superdisintegrants class novel agents have emerged recent years. Improving drug bioavailability pharmaceutical field is challenge. The inclusion superdisintegrants formulation enhances formulation's e...

Most commonly used conventional dosage forms are tablets and capsules. Compressed tablets are the most widely used dosage forms due to its numerous advantages. They are convenient, easy to administer, economic, tamper-proof, easy to packing and transport and more stable than other oral dosage forms [1]. Also tablets have certain special release profile products such as enteric or delayed releas...

The present study aims to formulate mouth dissolving tablets of montelukast sodium by direct compression method for the faster action, better absorption and improvement bioavailability drug in management Asthma. Total six formulations were developed with varying concentrations combination Crosspovidone Sodium starch glycolate as super disintegrating agents. prepared method. MDT evaluated variou...