OBJECTIVES There are scarce data from India validating scoring systems used to predict outcome in patients requiring mechanical ventilation. This study prospectively compared the organ system failure (OSF), the acute physiology and chronic health evaluation (APACHE) II, and the APACHE III, scores on patients requiring mechanical ventilation in the medical intensive care unit, to predict outcome...

Reliability based design optimization is a methodology for finding optimized designs that are characterized with a low probability of failure. The main objective in reliability based design optimization is to minimize a merit function while satisfying the reliability constraints. The reliability constraints are constraints on the probability of failure corresponding to each of the failure modes...

the main objective of endodontic therapy is the thorough mechanical and chemical cleansing of the entire root canal system and its complete obturation with an inert filling material. failure to find and fill a canal contributes toward the failure of endodontic therapy .the root canal anatomy of mandibular first molars is complex. studies of the morphologic structure of root canal systems have d...

Mechanical dyssynchrony is an important codeterminant of cardiac dysfunction in heart failure. Treatment, either medical, surgical, or by pacing, may improve cardiac function partly by improving mechanical synchrony. Consequently, the quantification of ventricular mechanical (dys)synchrony may have important diagnostic and prognostic value and may help to determine optimal therapy. Therefore, w...

UNLABELLED Implant-supported screw-retained fixed dental prostheses (FDPs) produced by CAD/ CAM have been introduced in recent years for the rehabilitation of partial or total endentulous jaws. However, there is a lack of data about the long-term mechanical characteristics. OBJECTIVE The aim of this study was to investigate the failure mode and the influence of extended cyclic mechanical load...

Recent advances of interfacial micromechanics in fiber reinforced composites using micro-Raman spectroscopy are given. The faced mechanical problems for interface design in fibrous composites are elaborated from three optimization ways: material, interface, and computation. Some reasons are depicted that the interfacial evaluation methods are difficult to guarantee the integrity, repeatability,...

Metallic glasses are known for their outstanding mechanical strength. However, the microscopic mechanism of failure in metallic glasses is not well-understood. In this article we discuss elastic, anelastic and plastic behaviors of metallic glasses from the atomistic point of view, based upon recent results by simulations and experiments. Strong structural disorder affects all properties of meta...

Case presentation 2: Patient is a 47-year-old man with a 12-year history of chronic heart failure due to idiopathic dilated cardiomyopathy. He now presents with New York Heart Association class IV symptoms that are refractory to medical therapy. At what point should we consider this patient for mechanical circulatory support? Mechanical circulatory support (MCS) is an important adjunct to the m...

OBJECTIVE To describe prognostic factors, clinical course, and hospital outcome of patients with chronic obstructive pulmonary disease admitted to an intensive care unit for acute respiratory failure. DESIGN Analysis of prospectively collected data. SETTING A multidisciplinary intensive care unit of an inner-city university hospital. PATIENTS Patients with chronic obstructive pulmonary di...

Finite element analysis (FEA), CT based structural rigidity analysis (CTRA) and mechanical testing is performed to assess the compressive failure load of rat tibia with simulated lytic defects. Twenty rat tibia were randomly assigned to four equal groups (n=5). Three of the groups included a simulated defect at various locations: anterior bone surface (Group 1), posterior bone surface (Group 2)...