holoprosencephaly is a rare congenital brain malformation resulting from failure of diverticulation and cleavage of primitive prosencephalon which occurs at 4 - 8th week of gestation and is usually associated with multiple midline facial anomalies. it is the most common forebrain developmental anomaly in humans with prevalence of 1/16,000 in live borns, an incidence as high as 1:250 in conceptu...

hyperpigmentation over face in a neonate is rare and the differentials for the same are also rare. congenital chickengunya, fungal and viral infections, drug rash are few differentials. chikungunya virus (chikv) infection manifesting in neonates is very rare. the prevalence of the entity was described only recently. we describe a neonate with hyperpigmentation on day 3 of life with stormy cours...

osteosarcoma (os) is the eighth common cancer of childhood and its incidence is 4 cases in one million in children younger than 14. facial os incidence is estimated between 8 and 10% of os cases. the main etiology of os is unknown, but various predisposing factors are proposed such as radiation, radiotherapy, some benign bone diseases like paget’s disease or fibrous dysplasia. there is a 5-year...

Several lines of evidence suggest that facial cues of adiposity may be important for human social interaction. However, tests for quantifiable cues of body mass index (BMI) in the face have examined only a small number of facial proportions and these proportions were found to have relatively low predictive power. Here we employed a data-driven approach in which statistical models were built usi...

STUDY OBJECTIVE To investigate the facial cues by which one recognizes that someone is sleep deprived versus not sleep deprived. DESIGN Experimental laboratory study. SETTING Karolinska Institutet, Stockholm, Sweden. PARTICIPANTS Forty observers (20 women, mean age 25 ± 5 y) rated 20 facial photographs with respect to fatigue, 10 facial cues, and sadness. The stimulus material consisted o...

Eruptive vellus hair cysts are disorders that present as cystic papules usually on the chest and extremities. Facial involvement is very rare in this disorder and few reports of facial eruptive vellus hair cysts have been presented till now.We present two cases of eruptive vellus hair cysts in a mother and her daughter with facial distribution.

conclusions we explain embryologic origin, differential diagnosis, other associated anomalies and its treatment by reviewing literature. introduction midline cleft of mandible, classified as tessier 30 clefts is extremely rare, with less than 100 reported cases in the latest studies. variations in severity and associated malformations have been reported before. case presentation in this report,...

objective angelman syndrome (as) is a genetically determined syndrome that has a unique behavioral phenotype. this syndrome is described as jerky ataxia and an unusual happy facial expression with pathological laughter. severe mental retardation is a unique feature of the syndrome, together with microbrachycephaly and abnormal electroencephalographic findings with or without clinical seizures. ...

Introduction: Synkinesis and facial asymmetry due to facial nerve palsy are distressing conditions that affect quality of life. Unfortunately, these sequelae of facial nerve palsy are unresolved. The aim of this study was to investigate the efficacy of a combination of biofeedback therapy and botulinum toxin A (BTX-A) injection for the management of synkinesis and asymmetry of facial muscles.  ...

Objective: The disability to recognize facial emotions is one of the behavioral problems in autistic children. This study was designed to evaluate the effect of education on the promotion of face recognition. Methods: This single-blind clinical trial study was conducted on children with autism. The participants were allocated with random sampling to the two groups. Autistic children in the int...