نتایج جستجو برای: f 18

تعداد نتایج: 633014  

Journal: :Nuclear Medicine and Molecular Imaging 2015

Journal: :Journal of Labelled Compounds and Radiopharmaceuticals 2018

Journal: :Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) 2016

Journal: :ACS medicinal chemistry letters 2016
Outi Keinänen Xiang-Guo Li Naveen K Chenna Dave Lumen Jennifer Ott Carla F M Molthoff Mirkka Sarparanta Kerttuli Helariutta Tapani Vuorinen Albert D Windhorst Anu J Airaksinen

A new (18)F-labeled tetrazine derivative was developed aiming at optimal radiochemistry, fast reaction kinetics in inverse electron-demand Diels-Alder cycloaddition (IEDDA), and favorable pharmacokinetics for in vivo bioorthogonal chemistry. The radiolabeling of the tetrazine was achieved in high yield, purity, and specific activity under mild reaction conditions via conjugation with 5-[(18)F]f...

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