INTRODUCTION Tuberculosis is one of the most important infectious causes of death worldwide. Ziehl-Neelsen staining of sputum has high specificity in tuberculosis endemic countries, but modest sensitivity which varies among laboratories. This study was set up to investigate the diagnostic value of serum Adenosine deaminase in diagnosis of tuberculosis. METHODS In a cross sectional and prospec...

background: on tuberculosis control standpoint, the treatment of children with tb is not considered a priority as they rarely transmit the disease and contribute little to the maintenance of the tuberculosis epidemic. therefor this study conducted to describe pediatric tb cases, and to identify pattern of risk factors in non-endemic communities materials and methods: the present cross- sectiona...

background: resistance to anti-tuberculosis (tb) drugs is a global problem. previous studies showed that the prevalence of primary mdr-tb is higher and has been increasing. the purpose of this study was to determine the primary drug resistance in strains isolated from patients with smear-positive of the new cases to anti-tb drugs. methods: in this cross-sectional study, 266 smear positive pulmo...

C-reactive protein and serum amyloid A protein levels were measured in 54 patients with pulmonary tuberculosis. The primary tuberculous complex was associated with an insignificant acute phase response, while post-primary tuberculosis without evidence of lung destruction caused modest increases in C-reactive protein and serum amyloid A protein. In most patients with post-primary pulmonary tuber...

Clinical presentations of Leishmania infection include visceral (most common form), cutaneous, mucocutaneous, mucosal and post-kala-azar dermal leishmaniasis. Mucosal form of leishmaniasis mostly involves oral and nasal mucosa. Rarely, laryngeal and pharyngeal mucosa may also be involved. Its concomitant presence with tuberculosis (TB), a disease rampant in India, is uncommon. Here we are repor...

INTRODUCTION Tuberculosis (TB) causes significant morbidity and mortality worldwide as one of the leading infectious diseases. In India, more than 1.8 million new cases occur every year. Rapid and accurate diagnosis of TB would improve patient care and limit its transmission. This study aimed to evaluate a dual target polymerase chain reaction (PCR) diagnostic assay to detect Mycobacterium tube...

BACKGROUND Tuberculosis (TB) is an infectious disease that remains a major cause of morbidity and mortality worldwide, yet the reasons why only 10% of people infected with Mycobacterium tuberculosis go on to develop clinical disease are poorly understood. Genetically determined variation in the host immune response is one factor influencing the response to M. tuberculosis. SP110 is an interfero...

INTRODUCTION Tuberculosis is a common multisystemic infectious disease caused by mycobacterium specie mainly mycobacterium tuberculosis. It affects everyone from Infants to the very aged. Tuberculosis usually affects the lungs (pulmonary tuberculosis) in 75% of cases, but in 25% of cases the other body systems: Central nervous system, lymphatic system, genitourinary system, gastrointestinal sys...