OBJECTIVES To evaluate the possible occupational hazard of environmental strains of opportunistic Pseudomonas aeruginosa on hydrocarbon contaminated sites during remediation, 2 multidrug-resistant isolates originating from environmental (soil and groundwater) samples were examined. MATERIAL AND METHODS Antibiotic resistance profiles of the examined 2 strains were determined by Etest® against ...

BACKGROUND AND OBJECTIVES Pseudomonas aeruginosa possesses a variety of virulence factors that may contribute to its pathogenicity. The aim of this study was to evaluate oprI, oprL and toxA genes for PCR identification of clinical P. aeruginosa. In order to find out any relation between special virulence factors and special manifestation of P. aeruginosa infections, we detected virulence factor...

The regeneration of articular cartilage, which scarcely shows innate self-healing ability, is a great challenge in clinical treatment. Stem cell-derived exosomes (SC-Exos), an important type of extracellular nanovesicle, exhibit great potential for cartilage regeneration to replace stem cell-based therapy. Cartilage regeneration often takes a relatively long time and there is currently no effec...

Background: Osteonecrosis of the femoral head (ONFH) is a common disease caused by many trauma factors and un-trauma factors. Among those factors, steroid-induced osteonecrosis (SNFH) accounted for large proportion mainly concentrated in young people. SNFH has been reported as an irreversible associated with damage blood vessels loss balance bone homeostasis. Circulating endothelial progenitor ...

[1] We investigated a Pi2 pulsation that occurred at 0538 UT on 20 September 1995, using data from ground stations and the ETS-VI and EXOS-D satellites. Since ground stations at L = 1.45 12.6 and the two satellites were located at 7–10 hours of magnetic local time (MLT), we could investigate characteristics of the morning side Pi2 pulsation in detail. We also examined geomagnetic field data fro...

Previously we reported that LIM1863 colorectal cancer (CRC) cells secrete three distinct extracellular vesicle subtypes - two subpopulations of exosomes (apical EpCAM-Exos and basolateral A33-Exos) and shed microvesicles (sMVs) - with distinct protein and miRNA signatures. Here, we extend our omics approach to understand the fundamental role of LIM1863-derived EVs by performing a comprehensive ...

Secreted microRNAs (miRNAs) enclosed within extracellular vesicles (EVs) play a pivotal role in intercellular communication by regulating recipient cell gene expression and affecting target cell function. Here, we report the isolation of three distinct EV subtypes from the human colon carcinoma cell line LIM1863--shed microvesicles (sMVs) and two exosome populations (immunoaffinity isolated A33...

Exosomes (exos) contain molecular cargo of therapeutic and diagnostic value for cancers other inflammatory diseases, but their potential periodontitis (PD) remains unclear. Dendritic cells (DCs) are the directors immune response have been extensively used in therapy. We previously reported a mouse model PD that custom murine DC-derived exo subtypes could reprogram toward bone-sparing or bone-lo...