Abstract High geotemperature seriously impacts personnel and equipment during railway expressway tunnel construction. In this study, the Nige in from Gejiu to Yuanyang Honghe Prefecture was used as an example. Firstly, automatic temperature recording devices were monitor variation characteristics of temperature. Afterward, at 5-10 days 150 after tunnel’s completion revealed. The results showed ...

The heat capacity Cp of an array of independent aluminum rings has been measured under an external magnetic field ~ H using highly sensitive ac-calorimetry based on a silicon membrane sensor. Each superconducting vortex entrance induces a phase transition and a heat capacity jump and hence Cp oscillates with ~ H . This oscillatory and non-stationary behaviour measured versus the magnetic field ...

Pocket proteins, including the retinoblastoma susceptibility gene product (pRB) and the related proteins p107 and p130, function at cell cycle regulatory steps that link cyclin/CDK-integrated positive and negative growth signals with E2F transcription factor activity on genes required for cell cycle progression. Protein complex formation between pocket proteins and members of the E2F family of ...

Understanding the mechanism and specificity of substrate binding in the cytochrome P450 (P450) superfamily is an important step toward explaining its key role in drug metabolism, toxicity, xenobiotic degradation, and several biosynthetic pathways. Here we investigate the ligand exit pathways and mechanisms of P450cam (CYP101), P450BM-3 (CYP102), and P450eryF (CYP107A1) by using random expulsion...

During the summer months, when northerly winds are blowing over the Aegean Sea the island of Crete modifies significantly the regional airflow as well as the pressure and temperature fields due to its complex topography. One of the major topographical elements of Crete Island is the major gap which is located between the two highest mountains Lefka Ori and Idi. On 24–25 August 2007 strong north...

Pulmonary vein electric isolation (PVI) is an effective therapy for atrial fibrillation. Bidirectional conduction block between left atrium (LA) and the pulmonary veins (PV) is an accepted end point for PVI. We report a case of rate-dependent unidirectional exit conduction from PV to LA after PVI by large area circumferential ablation, despite entrance and exit conduction block. A 63-year-old m...

The fission yeast scaffold molecule Sid4 anchors the septum initiation network to the spindle pole body (SPB, centrosome equivalent) to control mitotic exit events. A second SPB-associated scaffold, Cut12, promotes SPB-associated Cdk1-cyclin B to drive mitotic commitment. Signals emanating from each scaffold have been assumed to operate independently to promote two distinct outcomes. We now fin...