We have developed a rehabilitation programme at home and have investigated its effects on quality of life (QOL), lung function, and exercise tolerance in patients with chronic obstructive pulmonary disease (COPD). We studied 43 patients with severe airflow obstruction: forced expiratory volume in one second (FEV1) 1.3 +/- 0.4 l (mean +/- SD), FEV1/inspiratory vital capacity (IVC) 37 +/- 7.9%. A...

The case of an 8-year-old boy complaining easy tiredness, poor exercise tolerance and high CPK blood level is described. diagnosis glutaric aciduria type II was finally made.

This pilot study assessed the effects of cardiopulmonary exercise testing and cardiorespiratory fitness on plasma neuropeptide Y (NPY), allopregnanolone and pregnanolone (ALLO), cortisol, and dehydroepiandrosterone (DHEA), and their association with pain sensitivity. Medication-free trauma-exposed participants were either healthy (n = 7) or experiencing comorbid chronic pain/posttraumatic stres...

OBJECTIVE The Veterans Specific Activity Questionnaire (VSAQ) has been used to assess exercise tolerance. Nevertheless, there is no validated Chinese version. The aim of this study is to determine whether a questionnaire-based method using the Chinese version of VSAQ (the modified VSAQ) is a practical tool to assess exercise tolerance of Chinese elderly with coronary heart disease. METHODS On...

Study objectives: To study the short-term and long-term effects of combining activity training or lectures to exercise training on quality of life, functional status, and exercise tolerance. Design: Randomized clinical trial. Setting: Outpatient pulmonary rehabilitation center. Participants: Forty-three outpatients with COPD. Interventions: Patients were randomized to one of three treatment gro...

Henriksen, Erik J. Invited Review: Effects of acute exercise and exercise training on insulin resistance. J Appl Physiol 93: 788–796, 2002; 10.1152/japplphysiol.01219.2001.—Insulin resistance of skeletal muscle glucose transport is a key defect in the development of impaired glucose tolerance and Type 2 diabetes. It is well established that both an acute bout of exercise and chronic endurance e...

Transient ischemic attack results in tolerance to a subsequent severe brain ischemic attack, which is known as brain ischemic tolerance (BIT). In other words, preconditioning intervention leads to ischemic tolerance. The preconditioning intervention methods include ischemia, oxidative stress, and drug resistance to oxidative phosphorylation. Because of safety considerations, these methods are o...

To determine the constancy of hemodynamic and antianginal effects of the constant infusion of intravenous nitroglycerin (NTG) and their relationship to infusion rate and plasma NTG concentration, we administered maximal tolerated doses of intravenous NTG (range 10 to 120 ,g/min, mean = 52 + 33 ,ug/min) and placebo to 10 patients with chronic stable angina for 25 hr each in a randomized, double-...

xercise intolerance is a major clinical manifestation in patients with chronic heart failure (CHF). It was originally considered to be the result of a failure of perfusion to the exercising musculature and consequent early onset of intramuscular acidosis. Under this theory, cardiotonic agents were administered to improve symptoms and exercise tolerance in patients with CHF. However, the therapy...

OBJECTIVE The objective of this study was to analyze the effect of Spirulina and/or exercise training in the control of serum glucose homeostasis in diabetic rats. MATERIALS AND METHODS Young Wistar rats were induced to diabetes by intravenous alloxan administration and separated into four groups: diabetic control (DC), diabetic Spirulina (DS), diabetic exercise (DE) and diabetic exercise Spi...