A 15 year old boy with sickle cell disease developed intrahepatic cholestasis. A course of exchange transfusion successfully corrected the extreme hyperbilirubinaemia over one year. Upon stopping the exchange transfusion programme the hyperbilirubinaemia relapsed but transfusion was effective when reinstituted.

  Background: Reservation of blood leads to blood wastage if the blood is not transfused. Therefore, in some centers only blood type and screen are evaluated. In this study, the efficacy of a blood crossmatch-to-transfusion ratio was measured and then compared with the standard levels. Methods: This prospective study was conducted during one year in a university hospital. During this period, 39...

The acid-citrate-dextrose (ACD) solution used to preserve blood consists in effect of 2 parts trisodium citrate to 1 part citric acid. It forms a buffer solution such that the pH of bank blood less than 5 days old is, in our experience, 6 6 ± 0 * 2. It can be predicted, therefore, that infusion of ACD blood must lead to an initial acidosis, and that this will in due course be replaced by a meta...

Background. Factors that have been associated with severe hyperbilirubinaemia requiring exchange blood transfusion (EBT) are early discharge, late preterm birth and haemolytic disease. Early discharge is a common practice in neonatal care, so it important to identify audit neonates who received EBT, order modifiable factors. 
 Objectives. To describe the characteristics outcomes of infants...

objective to investigate association between nosocomial infection, blood products transfusion and microorganisms responsible in patients who hospitalized at icu (intensive care unit). patients and methods in this prospective study, 217 patients who were admitted to the icu of taleghani hospital between august 2010 and august 2011 were included. nosocomial infections were defined using the conta...

background: various adverse effects of homologous blood transfusion detected particularly in open heart surgery, in which it is frequently used, lead researchers to study on autologous blood use and to evaluate the patient’s blood better. due to the complications of homologous blood transfusion, development of techniques that utilize less transfusion has become inevitable. we aimed to evaluate ...

background and aim: postoperative hemorrhage is a common complication following coronary artery bypass graft (cabg) surgery. warming the patient may be effective on postoperative hemorrhage and blood transfusion. the main objective of this study was to determine the effect of postoperative active warming of the patient on hemorrhage and blood transfusion after off-pump cabg surgery. methods: th...

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INTRODUCTION The irradiation of blood components is used to inactivate T-lymphocytes to prevent transfusion-associated graft-versus-host (GVH) disease in susceptible recipients. X-irradiation can be used as an alternative to gamma irradiation and does not involve the use of a radioactive source. This study investigated the effect of X-irradiation on the quality of various red cell concentrates ...