نتایج جستجو برای: eudragit rspo

تعداد نتایج: 918  

Journal: :Acta pharmaceutica 2014
Gamal Mohamed El Maghraby Ehab Mostafa Elzayat Fars Kaed Alanazi

Alginate vehicles are capable of forming a gel matrix in situ when they come into contact with gastric medium in the presence of calcium ions. However, the gel structure is pH dependent and can break after gastric emptying, leading to dose dumping. The aim of this work was to develop modified in situ gelling alginate formulations capable of sustaining dextromethorphan release throughout the gas...

2011
Karan Malik Gurpreet Arora Inderbir Singh

Ofloxacin is a synthetic chemotherapeutic antibiotic used for treatment of a variety of bacterial infections, but therapy suffers from low patients' compliance due to its unpleasant taste. This study was aimed to develop taste masked microspheres of ofloxacin using Eudragit and to prepare orodispersible tablets of the formulated microspheres using natural superdisintegrant. Taste masking Eudrag...

2008
Md. A. Rahman J. Ali

The multiparticulate formulation of sodium para aminosalicylate for oral administration was developed by extrusion spheronization technique. Microcrystalline cellulose was used as filler in concentration of 14.4% w/w. Pellets were coated with Eudragit L 30 D-55 using fluidized bed processor. Different weight gains of acrylic polymer were applied onto the pellets and evaluated for in vitro disso...

Journal: :European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2008
Nizar Al-Zoubi Hatim S Alkhatib Yasser Bustanji Khaled Aiedeh Stavros Malamataris

Sustained-release of buspirone HCl (BUH) was attempted by spray drying after dissolving in two commercially available aqueous polymeric dispersions (Eudragit RS 30 D or Kollicoat SR 30 D) at five different drug:polymer ratios (1:1, 1:2, 1:3, 1:6 and 1:9). The produced spray-dried agglomerates were evaluated in terms of their particle size and morphology, production yield, encapsulation efficien...

Journal: :research in pharmaceutical sciences 0
sara salatin 1research center for pharmaceutical nanotechnology, tabriz university of medical science, tabriz, i.r. iran. 2student research committee, tabriz university of medical science, tabriz, i.r. iran. jaleh barar 1research center for pharmaceutical nanotechnology, tabriz university of medical science, tabriz, i.r. iran. 3department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, i.r. iran. mohammad barzegar-jalali 3department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, i.r. iran. khosro adibkia 3department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, i.r. iran. 4drug applied research center and faculty of pharmacy, tabriz university of medical sciences, tabriz, i.r. iran. farhad kiafar 3department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, i.r. iran. 5zahravi pharmaceutical company, tabriz, i.r. iran. mitra jelvehgari 3department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, i.r. iran. 4drug applied research center and faculty of pharmacy, tabriz university of medical sciences, tabriz, i.r. iran.

rivastigmine hydrogen tartrate (rht), one of the potential cholinesterase inhibitors, has received great attention as a new drug candidate for the treatment of alzheimer's disease. however, the bioavailability of rht from the conventional pharmaceutical forms is low because of the presence of the blood brain barrier. the main aim of the present study was to prepare positively charged eudragit r...

Journal: :iranian journal of basic medical sciences 0
reza enayatifard pharmaceutical sciences research center, mazandaran university of medical sciences, sari, iran department of pharmaceutics, faculty of pharmacy, mazandaran university of medical sciences, sari, iran aiding mahjoob department of pharmaceutics, faculty of pharmacy, mazandaran university of medical sciences, sari, iran pouneh ebrahimi department of chemistry, faculty of basic sciences, golestan university, gorgan, iran pedram ebrahimnejad pharmaceutical sciences research center, mazandaran university of medical sciences, sari, iran department of pharmaceutics, faculty of pharmacy, mazandaran university of medical sciences, sari, iran

objective(s): a box-behnken design was used for evaluation of eudragit coated diclofenac pellets. the purpose of this work was to optimize diclofenac pellets to improve the physicochemical properties using experimental design. materials and methods: diclofenac was loaded onto the non-pareil beads using conventional coating pan. film coating of pellets was done at the same pan. the effect of pla...

Behzad Taghipour Mohammad Ali Dabbagh,

     Ibuprofen solid dispersions were prepared by the solvent and fusion-solvent methods using polyethylene glycol (PEG), polyvinylpyrrolidone (PVP), eudragit RS PO, eudragit RL PO and hydroxypropylmethylcellulose (HPMC) as carriers to improve physicochemical characteristics of ibuprofen. The prepared solid dispersions were evaluated for the flowability, solubility characteristics and dissoluti...

2012
Biresh Kumar Sarkar Vikram Sharma

The present study is the development of colon targeted matrix tablets of the drug flurbiprofen, a NSAIDS of the class of Ibuprofen designed to prolonged the release for sustained effect. Different formulation (F1 TO F9) batches were made with the help of different polymers and their different proportions (Guar Gum, Eudragit RL, Eudragit RS ) with the help of Wet granulation techniques. The prep...

Journal: :Acta pharmaceutica 2012
Pravin K Pawar Rajesh Katara Dipak K Majumdar

The objective of the present investigation was to prepare and evaluate ocular inserts of moxifloxacin. An ocular insert was made from an aqueous dispersion of moxifloxacin, sodium alginate, polyvinyl alcohol, and dibutyl phthalate by the film casting method. The ocular insert (5.5 mm diameter) was cross-linked by CaCl2 and was coated with Eudragit S-100, RL-100, RS-100, E-100 or L-100. The in v...

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