Microspheres containing indinavir sulfate were prepared by the emulsion solvent evaporation technique using surfactant sorbitan monooleate 80. The evaluation reports for Fourier-transform infrared spectroscopy and X-ray diffraction taken to see whether altered physicochemical features of produced microspheres. Scanning electron microscopy was used observe surface topography When 80 employed at ...

Pharmaceutical companies today face a growing demand for more complex drug designs. In the past few decades, a number of probabilistic models have been developed, for the purpose of giving a better insight into the microscopic features of these complex designs. Of particular interest are those models that simulate controlled release systems to provide targeted dose delivery. Controlled release ...

Objective: This study is to formulate Nebivolol into a Pulsatile liquid, solid composite compression coated tablet, which will delay the release of drug in early morning hypertension conditions. Methods: The tablet was formulated and compressed with ethylcellulose coating polymer. percent vitro liquid tested. Based on disintegration time wetting time, LCS2, LCS3, LSC6, LCS7 LCS12 formulations w...

       This research was conducted to investigate the physico-mechanical characteris-tics of the ethylcellulose-based coating membranes plasticized with different weight percents of dibutyl sebacate. In this experiment, free thin polymer sheetings of the sample formulations, by incorporating incremental weight percents of the plasticizer, were prepared employing a revised casting method of dela...

The purpose of this investigation is to formulate and evaluate the antihypertensive drug propranolol hydrochloride sustained-release bilayer tablets. In formulation, one layer provides a loading dose through immediate release other maintenance for up 12 h controlled release. Different quantities polymers such as Kyron T-314, Hydroxypropyl methylcellulose- K4M, ethyl cellulose were used make bi-...