A refined diet supplemented with Japanese-style fermented soy sauce (shoyu) inhibits benzo[a]pyrene-induced forestomach neoplasia in mice (Cancer Res., 51:2940-2942, 1991). In the present study, soy sauce was extracted with ethyl acetate. The soluble fraction contained flavor/aroma compounds and antioxidants, whereas amino-carbonyl compounds that impart color were concentrated in the ethyl acet...

BACKGROUND The plant Launaea procumbens belongs to the family Asteraceae and traditionally used in the treatment rheumatism, kidney, liver dysfunctions and eye diseases. In the present study Phytochemical analysis and fractions of methanolic extract of L. procumbens leaves were tested in vitro for their cytotoxicity. OBJECTIVES Phytochemical analysis and cytotoxic activity of methanolic extra...

Crystals of the title compound, C(22)H(29)NO(5)·C(4)H(8)O(2), {[systematic name: (2R,3R,5R,5aS,6R,8aR,9S)-(5Z)-5-[3-butyl-tetra-hydro-6-methyl-2,5-methano-4,3,8a-[1]propan-yl[3]yl-idene-furo[3,2-f][1,4]oxazepin-7(5H)-yl-idene]-4-meth-oxy-3-methyl-furan-2(5H)-one ethyl acetate solvate} were isolated from the root extracts of Stemona aphylla (Stemonaceae). The structure closely resembles those of...

The results of our previous investigations on extracts of selected marine algae showed that Caulerpa peltata and Padina gymnospora had more promising antiproliferative and antioxidant activities than Gelidiella acerosa and Sargassum wightii. Based on these results, the more active chloroform extract of C. peltata and ethyl acetate extract of P. gymnospora were further analyzed for their constit...

..A.LMOST ALL the neutral urinary 17-ketosteroids are conjugated with either sulfuric or glucuronic acids. These conjugates can be cleaved by strong acids at elevated temperatures (1), or by solvolysis in either ethyl acetate or tetrahydrohiran, each containing perchioric acid (2). Selective hydrolysis of steroid-glucuronosicles is achieved with $-glucuromi_ idase, although in some 1i1#{149}ill...

The aim of the study was to examine the ability of Göttingen minipigs to acquire an olfaction-based operant conditioning task and to determine the detection threshold for ethyl acetate and ethanol. We used an automated olfactometer developed for rodents to train and test 14 pigs. Odor sampling and reliable responding were obtained after three to fifteen 160-trial sessions. Successful transfer o...

Exposure to environmental pollutants often leads to an upsurge in the production of reactive oxygen species (ROS). ROS oxidize cellular fatty acids to produce lipid peroxyl radicals, subsequently transformed into lipid peroxides, which decrease membrane fluidity and increase the activity of various enzymes implicated in degenerative diseases and cancer formation. Edible plants that contain exog...

The chloroform (4.20% w/w), ethyl acetate (4.23% w/w) and aqueous decoction (12.11% w/w) extracts of the aerial parts of A. indica were screened for the antiepileptic activity against maximal electroshock (MES) model and pentylenetetrazole (PTZ) models at doses of 200, 400 mg/kg, po once. Phenytoin and diazepam (25 and 2 mg/kg, ip) were used as standard drugs in MES and PTZ model, respectively....

Column Zorbax silica, 25 cm 4.6 mm internal diameter (7 m) S5W uncoated silica, 25 cm 4.6 mm internal diameter (5 m) Eluent Hexane}ethyl acetate, 95 : 5 CO2 modified with small amounts of methanol Flow rate 1.6 mL min 1 2 mL min 1 for 4 min, then gradient of 2 up to 5 mL min 1 thereafter held constant Programme Isocratic P"100 atm, T"403C; modifier, 1.5%min 1 from 10% to 30% thereafter held con...