Diets rich in polyunsaturated fatty acids lower plasma HDL cholesterol concentrations when compared to diets rich in saturated fatty acids. We investigated the mechanistic basis for this effect in the hamster and sought to determine whether reduced plasma HDL cholesterol concentrations resulting from a high polyunsaturated fat diet are associated with a decrease in reverse cholesterol transport...

2,6-diaminopyridine is extensively used as a pharmaceutical intermediate and a hair dye coupler as oxidation formulations. It is soluble in protic solvents. Primary and secondary amines are N-methylated by various methods such as direct alkylation of amines with Hofmann mechanism, but in many of these methods due to overalkylations, we earn a mixture of amino products. Consequently, they aren't...

The objective of this research work is to compare the findings two techniques synthesis (solid state and solution based synthesis) in order know whether results are similar or not also determine if introduction metal ion increase decrease activity drug. From spectral studies, it revealed that ligand act as bidentate which coordinated central through carbonyl acid ester. elemental analysis data ...

An efficient synthesis of 3,4-dihydro-2(1H)-pyrimidinones using NanoMgAl2O4as the catalyst from an aldehyde, βKeto ester, and urea under solvent-free conditions is described.