Multiple primary malignancies are not rare. While metachronous triple cancers are rare and a triple tumor case involving maxillary sinus and tympanic membrane is exceptionally rare. We present such an extremely rare case with the index tumor of adenoid cystic carcinoma of the maxillary sinus and 14 years later esophageal cancer was observed as a metachronous tumor. One year after esophageal can...

this is a case report concerning a 60 years old man who lived for a short period in an endemic area of khuzestan province (neighboring province of persian gulf in iran) for approximately 20 years ago. recently he referred to the urology department of kerman university of medical sciences with hematuria and dysuria. in the sonography a polypoid mass on the bladder floor was observed. in the cyst...

a 2-year-old male hamster was presented because of left facial swelling and salivation. necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. in histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. vacoulation o...

head and neck squamous cell carcinoma, including oral squamous cell carcinoma (oscc) is the sixth most common cancer in the human population. despite significant efforts committed in treatment of oscc the overall survival rate of oscc has not improved significantly. activating mutations in the fibroblast growth factor receptor 3 (fgfr3) genes are responsible for some human cancers, including bl...

purpose: to report a case of isolated corneal squamous cell intraepithelial neoplasia in a patient with unilateral dry eye symptoms. case report: a 48 year old man presented with history of thermal corneal injury in his left eye two years ago, with decreased visual acuity and dry eye symptoms a short time thereafter. he was treated for dry eye with no improvement in symptoms. upon presentation,...

diaphragmatic hernia, secondary to transhiatal esophagectomy, appears to be a relatively infrequent diagnosis. patients may be asymptomatic or present with various symptoms. diagnosis of this condition requires a high index of suspicion. the most common cause of diaphragmatic hernia is widened esophageal hiatus during surgery; therefore, narrowing the hiatus can prevent conduit herniation. here...

objective: systemic sclerosis (ss) is a chronic autoimmune disease of connective tissue, which involves skin and internal organs, and results in collagen deposition and fibroblasts activation. studies have reported a higher risk of malignancy in patients with progressive systemic sclerosis (pss).the aim of this study is to report a case of tongue squamous cell carcinoma (scc) in a patient with ...

BACKGROUND We have previously hypothesized that preterm birth or impaired fetal growth may cause esophageal adenocarcinomas through gastroesophageal reflux early in life. In this study, we aimed to test if there is an association between gestational duration and birth weight on the one hand, and risk of esophageal and cardia adenocarcinoma on the other. METHODS We conducted a nested case-cont...

The Fifth edition of the World Health Organization classification digestive system and American Joint Committee on Cancer staging manual contain substantial refinements information for esophageal tumors. epithelial tumors esophagus are classified as benign, dysplasia, malignant groups. Dysplasia is divided into Barrett dysplasia squamous graded either low-grade or high-grade. Malignant often ad...