. Demonstrate an understanding of the natural history and manifestations of reflux disease . Evaluate the role of diagnostic testing such as endoscopy, esophageal manometry, ambulatory pH monitoring, and impedance-pH monitoring in the management of patients with gastroesophageal reflux disease . Evaluate the options for treatment of patients with complicated and uncomplicated reflux disease.

BACKGROUND Gastroesophageal reflux disease (GERD) is comprised of a spectrum of related disorders, including hiatal hernia, reflux disease with its associated symptoms, erosive esophagitis, peptic stricture, Barrett's esophagus, and esophageal adenocarcinoma. Besides multiple pathophysiological associations among these disorders, they are also characterized by their comorbid occurrence in ident...

PURPOSE To evaluate the prevalence of esophageal reflux-induced symptoms after gastrectomy owing to gastric cancer and assess the relationship between esophageal reflux-induced symptoms and quality of life. MATERIALS AND METHODS From January 2012 to May 2012, 332 patients were enrolled in this cross-sectional study. The patients had a history of curative resection for gastric cancer at least ...

HYPOTHESIS Risk factors for the presence and extent of Barrett esophagus (BE) can be identified in patients with gastroesophageal reflux disease (GERD). DESIGN Case-comparison study. SETTING University tertiary referral center. PATIENTS Five hundred two consecutive patients with GERD documented by 24-hour esophageal pH monitoring and with complete demographic, endoscopic, and physiologica...

BACKGROUND Motility disturbances of the esophagus and gastroesophageal reflux disease (GERD) are observed frequently in children after repair of congenital esophageal atresia with distal tracheoesophageal fistula (EA/TEF). Recently, in many pediatric surgical centers, thoracoscopic repair was introduced, which theoretically would change the postoperative course. OBJECTIVES The goal of the stu...

BACKGROUND Patients with gastroesophageal reflux and Barrett esophagus may represent a group of patients with poorer postoperative outcomes. It has been suggested that such patients should undergo open rather than laparoscopic antireflux surgery. HYPOTHESIS The laparoscopic approach to antireflux surgery is appropriate treatment for patients with Barrett esophagus who have symptomatic gastroe...

. Demonstrate an understanding of the natural history and manifestations of reflux disease . Evaluate the role of diagnostic testing such as endoscopy, esophageal manometry, ambulatory pH monitoring, and impedance-pH monitoring in the management of patients with gastroesophageal reflux disease . Evaluate the options for treatment of patients with complicated and uncomplicated reflux disease.

The purpose of this study was to develop an acute animal model of reflux esophagitis, which would be suitable to induce the esophageal damage caused by gastric acid reflux, thus mimicking the esophageal injury of human gastroesophageal reflux disease (GERD). Global research indicates that GERD is rapidly increasing among the world's population. NSAIDs are known to induce gastrointestinal damage...

BACKGROUND AND AIMS Alkaline reflux esophagitis is a complication that might develop in patients with total gastrectomy. The aim of the study was to analyze the prevalence and severity of reflux esophagitis and the occurence of complications (Barrett's esophagus and esophageal stenosis) in patients with total gastrectomy and Roux en Y esojejunostomy. METHODS 92 patients with total gastrectomy...