BACKGROUND/AIMS Stricture formation is a common complication after endoscopic mucosal resection. Predictors of stricture formation have not been well studied. METHODS We conducted a retrospective, observational, descriptive study by using a prospective endoscopic mucosal resection database in a tertiary referral center. For each patient, we extracted the age, sex, lesion size, use of ablative...

BACKGROUND Cyclin E is a cell cycle regulator which is critical for driving G1/S transition. Abnormal levels of cyclin E have been found in many cancers. However, the level changes of cyclin E in esophageal adenocarcinoma and its precancerous lesion have not been well studied. Here, we focus on the gene amplification and expression of cyclin E in these lesions, and aim to ascertain the relation...

Cyclooxygenase (COX) and vascular endothelial growth factor (VEGF) play important roles in animals, especially in the carcinogenesis and the metastasis of the tumor. In the current issue of Life Science Journal, Xing et al offer the article of Changes of COX-2 and VEGF expressions in esophageal precancerous and cancerous lesions from the patients at high incidence area in Henan province. This a...

Average CT (ACT) and PET have a similar temporal resolution and it has been shown to improve registration of the CT and PET data for PET/CT imaging of the thorax. The purpose of this study was to quantify the effect of ACT attenuation correction on PET for gross tumor volume (GTV) delineation with standardized uptake value (SUV) for liver and esophageal lesions. Our study included 48 colorectal...

It is known that upper gastrointestinal bleeding has many causes, esophageal and gastric lesions being the most frequent. Esophageal varices, the most common esophageal disease involved in the appearance of gastrointestinal bleeding, are due to portal hypertension, which is generated by different causes, including portal cavernoma [1,2]. It is also known that portal cavernoma can have many caus...

Esophageal intramural pseudodiverticulosis (EIP) is a rare benign disease that is characterized by multiple tiny flask-shaped outpouching lesions of the esophageal wall. The etiology is unknown, but the pathologic findings include dilatation of excretory ducts of submucosal glands. The predominant symptom is dysphagia, and esophageal stricture occurs frequently. Diseases such as diabetes mellit...

BACKGROUND The present study aimed to evaluate apoptosis and cell proliferation alterations in esophageal benign lesions in comparison to esophageal carcinomas. MATERIALS AND METHODS Immunohistochemistry was performed for caspase-3 protein (CPP32) and Ki-67 antigen expression in the esophageal mucosa from patients with Chagas disease (CD) with and without megaesophagus (CM), chronic esophagit...

treatment of choice and an alternative to esophagectomy in the treatment of Barrett’s esophagus with early neoplasia and superficial esophageal cancer limited to the mucosal layer.1 EMR of larger lesions requires piecemeal resection which allows the risk of higher local recurrence than in cases with en bloc resection. Endoscopic submucosal dissection (ESD) has been successfully applied for the ...

A 51-year-old man was admitted to our hospital with hematemesis after swallowing a chicken bone. An endoscopy was performed, which showed a large submucosal hematoma in the esophagus, which extended from 15cm down to the esophagogastric junction. The esophageal lumen was occupied by the hematoma. No active bleeding or foreign body was seen (●" Fig.1;●" Video 1). The findings on examination and ...