BACKGROUND Treatment of achalasia is focused on decreasing the resting lower esophageal sphincter by either pneumatic dilation or surgical myotomy. When patients symptomatically relapse after one or more pneumatic dilations, then one explanation is to consider the possibility of pseudoachalasia as the diagnosis. CASE REPORT We present a rare case of an elderly patient with a presentation of c...

Achalasia is an esophageal motility disorder that is accepted as a risk factor for the development of cancer. Especially in megaesophagus, chronic irritation of foods and bacterial overgrowth may contribute to the formation of high-grade dysplasia and squamous cell carcinoma. We present a case of advanced stage achalasia with high-grade dysplasia detected three years after a cardiomyotomy opera...

c 2016 The Korean Society of Neurogastroenterology and Motility J Neurogastroenterol Motil, Vol. 22 No. 2 April, 2016 www.jnmjournal.org TO THE EDITOR: We would like to thank Huang and Rezaie for their interesting comments. As the authors are well aware of, diagnosis of Jackhammer esophagus requires normal integrated residual pressure (IRP) and at least 20% of the swallows with distal contracti...

Intraluminal manometric studies were carried out in 19 patients with untreated achalasia and in 20 normals. Lower esophageal sphincter (LES) pressure was 50.5 +/-4.6 mm Hg in patients with achalasia as compared with 19.4 +/-1.3 mm Hg in the normal group. In both groups, the LES pressure was lowered when exogenous 0.1 N HCl was placed into the stomach. Although the nadir of pressure attained wit...

BACKGROUND Although achalasia is a relatively rare disease in pediatric age group, it must be considered for differential diagnosis of esophageal disorders in children with positive family history even in the absence of typical clinical manifestations. CASE PRESENTATION A 5-month old boy was hospitalized for cough and mild respiratory distress. Because of positive history of achalasia in his ...

Idiopathic achalasia is a motility disorder affecting the lower esophageal sphincter. Dysphagia hallmark symptom, but patients may exhibit other symptoms. The aim of this review to compare symptoms globally. PubMed and Google Scholar were filtered from 1952–2021 with search terms achalasia, epidemiology, diet, countries, genetics. A total 14 articles addressed demographics, symptom profiles, ge...

The risk of esophageal perforation following endoscopic balloon dilation for achalasia is in the range of 1%-5%, with a mortality rate of 1%-20%. Perforations need to be recognized early, and, if reasonable, an immediate endoscopic repair should be pursued quickly. Herein, we report a case of successful endoscopic closure by clipping of a large iatrogenic perforation in a patient with achalasia...

Background: Esophageal achalasia is a motility disorder characterized by lack of esophageal peristalsis and failure the lower sphincter (LES) to relax. Patients typically present dysphagia for both solids liquids, regurgitation, retrosternal chest pain, cough, aspiration, weight loss heartburn, which affect their quality life. Objective: To determine whether High-resolution manometry (HRM) subt...

is an idiopathic motility disorder that results from degeneration of the myenteric plexus in the wall of the esophagus and the lower esophageal sphincter (LES). 1 In esopha-geal manometry, achalasia is characterized by impaired relaxation of LES and loss of peristalsis in the body of the esophagus. Achalasia results in severe dysphagia for solids and liquids. Additional symptoms can also develo...