An investigation of the degradation of cholesterol by soil microorganisms has shown that the initial oxidation of this compound is due, both in situ and in pure culture, to the activities of members of a single genus, Proactinomyces (Turfitt, 1944a). During the cultural work a considerable number of organisms, both molds and bacteria, persisted with the strains of Proactinomyces through many su...

shiga toxin-producing escherichia coli (stec) are food-borne pathogens primarily associated with the consumption of contaminated ground beef and are an important food safety concern worldwide. stec has been found to produce a family of related cytotoxins known as shiga toxins (stxs). shiga toxins have been classified into two major classes, stx1 and stx2. a single strains of stec can produce st...

BACKGROUND The first hours after antigen stimulation, interactions occur influencing the outcome of the immunological reaction. Immunoglobulins originate in blood and/or are locally synthesized. The transfer of Ig isotypes (Igs) in the udder has been studied previously but without the possibility to distinguish between the endothelium and the epithelium. The purpose of this study was to map the...

conclusions etec and eaggec were the most detected e. coli among stool and uti samples, emphasizing the need to dedicate more health care attention to this group. in addition, our phylogenetic study may be helpful in figuring out the infection origin and for epidemiological studies. nonetheless, more research studies with larger sample sizes are suggested for confirming our results. results ove...

background: in the recent years, there has been an increasing interest in secretory production of recombinant proteins, due to its various advantages compared with intracellular expression. signal peptides play a critical role in prosperous secretion of recombinant proteins. accordingly, different signal peptides have been assessed for their ability to produce secretory proteins by trial-and-er...

conclusions: e. coli herb-resistance plasmid can replicate and be expressed in s. aureus. results: the identified 45 kb herb-resistance plasmid could be transferred from e. coli cp9 isolates to e. coli dh5α. as a consequence e. coli dh5α transconjugant mic increased from 0.0125 g/ml to 0.25 g/ml. the plasmid was easily transferred from e. coli cp9 strain to s. aureus rn450rf with a mean transfe...

background: targeting of cd20 antigen with monoclonal antibodies has become the mainstay in the treatment of non-hodgkin's lymphomas and immunotherapeutic depletion of malignant b cells. accessibility of antigen is one of the crucial factors in development of monoclonal antibodies against this antigen. one major problem in expression of full length cd20 is aggregation and misfolding. there...