Genital ulcer disease (GUD) is well recognised in the developing world as a co-factor for heterosexual HIV transmission. Men with GUD are an important high frequency HIV transmitter core group in the general population but few interventions have targeted such individuals so far. Donovanosis is an uncommon GUD with low infectivity characterised by large ulcers that bleed readily and has been ide...

Deep infection is a serious and costly complication of total knee arthroplasty (TKA), which can increase patient morbidity and compromise functional outcome and satisfaction. Two-stage revision with an interval of parental antibiotics has been shown to be the most successful treatment in eradicating deep infection following TKA. We report a large series by a single surgeon with a highly special...

Mass-vaccination campaigns are an important strategy in the global fight against poliomyelitis and measles. The large-scale logistics required for these mass immunisation campaigns magnifies the need for research into the effectiveness and optimal deployment of pulse vaccination. In order to better understand this control strategy, we propose a mathematical model accounting for the disease dyna...

Variola (smallpox) virus is classified as class A of potential biological weapons, due to its microbiological, genetic, antigenic and epidemiological characteristics. The potential danger is more real because vaccination against smallpox has stopped since disease eradication in 1979. That is why we want to share our unique, rich experience and acquired knowledge in the fight against this highly...

In response to identified deficiencies in the passive surveillance system for measles in Victoria and the move towards local disease elimination and global disease eradication, a system of enhanced measles surveillance was introduced in 1997. Each case is contacted and a structured telephone questionnaire is completed, collecting information on symptomatology and encouraging serological confirm...

On March 20, 2000, a suspected vesicular disease in cattle was reported to the National Veterinary Research and Quarantine Service (NVRQS) of the Republic of Korea. This represented the index case of a foot-and-mouth disease (FMD) outbreak, which spread through several provinces. The Republic of Korea had been free of FMD for 66 years prior to the reintroduction of the virus and had recently su...

Pakistan is one of the two endemic countries for polio, reporting co-circulation WPV1 and cVDPV2. classified by International Health Regulations (IHR) as a state infected with Wild Poliovirus type 1 (WPV1) circulating Vaccine derived poliovirus 2 (cVDPV2) potential risk international spread. We describe an ongoing outbreak in North Waziristan district southern Khyber Pakhtunkhwa (KP) province l...

Foreword 5 A B J E C t poverty is evidence of the failure of modern societies to adopt social and economic strategies that benefit all people. It deprives individuals of their dignity, and denies them the opportunity to be participating citizens, with a sense of self-respect and a feeling of well-being. By 1995, it was estimated that 1.3 billion people were living on less than one dollar per da...