No ano 2000, os chefes de Estado de 182 países decidiram intensificar esforços para combater a extrema pobreza e promover o desenvolvimento humano. Suas resoluções foram incluídas na Declaração do Milênio e deram origem aos chamados “Objetivos de Desenvolvimento de Milênio”. Esses objetivos cobrem aspectos amplos do desenvolvimento econômico e social e incluem também metas relacionadas à saúde,...

Introduction: 99mTc-MIBI has been proposed for use as an imaging agent for various tumors, including breast cancer, lung cancer, lymphomas, melanomas and brain neoplastic lesions. Brain tumors are very common and radiotherapy being major part of treatment following surgery. After radiotherapy, deteriorating clinical status can be due to either radiation necrosis or recurrent tumor. Comput...

A 37 year old gentleman with recurrent chest pain and dyspnoea on exertion was referred for cardiac CT examination after an equivocal exercise stress test.

Visual interpretation is considered the gold standard for amyloid scans in clinical practice. However, dichotomous classification of deposition by visual reading always results bias due to rater experience. Therefore, there a need more lenient and flexible amyloid-equivocal A total 461 participants were included this study. Amyloid glucose positron-emission tomography was performed, neuropsycho...

BACKGROUND Breast cancers that overexpress the human epidermal growth factor receptor 2 (HER2) are eligible for effective biologically targeted therapies, such as trastuzumab. However, accurately determining HER2 overexpression, especially in immunohistochemically equivocal cases, remains a challenge. Manual analysis of HER2 expression is dependent on the assessment of membrane staining as well...

Fine needle aspiration (FNA) cytology is now an integral part of the pre-operative investigation of breast lesions and the therapeutic protocol is today often planned on the basis of cytodiagnosis. However, from time to time the cytological picture may be equivocal or inconclusive. In recent years, nucleolar organizer region (NOR) scores have been explored for potential value in the diagnosis o...