نتایج جستجو برای: eptifibatide
تعداد نتایج: 434 فیلتر نتایج به سال:
Protein disulfide isomerase (PDI) catalyzes the oxidation reduction and isomerization of disulfide bonds. We have previously identified an important role for extracellular PDI during thrombus formation in vivo. Here, we show that endothelial cells are a critical cellular source of secreted PDI, important for fibrin generation and platelet accumulation in vivo. Functional PDI is rapidly secreted...
BACKGROUND The significance of thrombocytopenia in patients experiencing an acute coronary syndrome (ACS) has not been examined systematically. We evaluated this condition in a large non-ST-elevation ACS clinical trial, with particular interest paid to its correlation with clinical outcomes. METHODS AND RESULTS Patients presenting without persistent ST elevation during an ACS were randomized ...
• Objective: To review the clinical trials of glycoprotein IIb/IIIa (GPIIb/IIIa) inhibitors for unstable angina or non–ST segment elevation myocardial infarction (MI) and to provide a practice guide for the use of these agents in this setting. • Methods: Clinical trials relating to GPIIb/IIIa antagonists and acute coronary syndromes were identified from a MEDLINE search of articles published be...
Protein disulfide isomerase (PDI) catalyzes the oxidation reduction and isomerization of disulfide bonds. We have previously identified an important role for extracellular PDI during thrombus formation in vivo. Here, we show that endothelial cells are a critical cellular source of secreted PDI, important for fibrin generation and platelet accumulation in vivo. Functional PDI is rapidly secreted...
Aim of the work: To evaluate the efficacy and safety of bolus only intra coronary platelet glycoprotein GP IIb/IIIa receptor antagonists combined with thrombus-aspiration during percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI). Patient and Methods: 25 consecutive STEMI patients treated by primary PCI including thrombus aspiration were prospectively ...
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