Enzyme-linked immunosorbent assays (ELISAs) were developed for detection of immunoglobulin G (IgG) and IgM antibodies to Venezuelan equine encephalomyelitis (VEE) virus in vaccinated and naturally infected humans. A total of 441 sera found negative for VEE antibodies by plaque reduction neutralization were examined by IgG ELISA and gave a 1.0% false-positive rate; no false-positives were found ...

Methods Vascular ejection efficiency (VEE) is proportional to the dimensionless ratio of aortic diameter to wavelength of the transmitted blood pulse. The wavelength of ejected blood is proportional to blood wave velocity divided by blood wave frequency measured using phase velocity mapping (PVM) applied to the ascending aorta. Left ventricular function and aortic PVM data were retrospectively ...

Recent studies have indicated that epizootic Venezuelan equine encephalitis (VEE) viruses can evolve from enzootic, subtype ID strains that circulate continuously in lowland tropical forests (A. M. Powers, M. S. Oberste, A. C. Brault, R. Rico-Hesse, S. M. Schmura, J. F. Smith, W. Kang, W. P. Sweeney, and S. C. Weaver, J. Virol. 71:6697-6705, 1997). To identify mutations associated with the phen...

Given an ideal I on ω let a(I) (ā(I)) be minimum of the cardinalities of in nite (uncountable) maximal I-almost disjoint subsets of [ω]. We show that a(Ih) > ω if Ih is a summable ideal; but a(Z~ μ) = ω for any tall density ideal Z~ μ including the density zero ideal Z. On the other hand, you have b ≤ ā(I) for any analytic P -ideal I, and ā(Z~ μ) ≤ a for each density ideal Z~ μ. For each ideal ...

We have previously characterized with monoclonal antibodies (MAbs) seven unique epitopes on the two envelope glycoproteins of Venezuelan equine encephalomyelitis (VEE) virus vaccine strain TC-83. The epitopes important in protection from VEE virus infection were determined in passive antibody transfer studies, with virulent VEE (Trinidad donkey) virus as the challenge virus. Selected high-avidi...

A variety of vaccine platforms are under study for development of new vaccines for measles. Problems with past measles vaccines are incompletely understood and underscore the need to understand the types of immune responses induced by different types of vaccines. Detailed immune response evaluation is most easily performed in mice. Although mice are not susceptible to infection with wild type o...

1. Abstract 2. Introduction 2.1. History and successes of cancer immunotherapy 2.2. Viruses and cancer therapy 3. Identification of tumor associated antigens 4. Ideal properties of an antigen delivery system 4.1. Why are viral vectors suitable for delivering TAAs? 5. Poxvirus vectors 5.1. Vaccinia virus 5.1.1. Use of vaccinia viral vectors to deliver tumor antigens 5.1.1.1. Carcinoembryonic ant...

The experiments described were designed to provide information on the infectivity of Venezuelan equine encephalitis (VEE) virus for birds by the respiratory route. Laboratory studies by Chamberlain (2) showed that wild birds, including pigeons, could be infected with VEE virus by mosquito bite or by subcutaneous (sc) injection of virus. Overt signs of disease were absent in avian hosts, but vir...

Abstract We develop a scheme to construct the Hamiltonians of the lambda, vee and cascade type of three-level configurations using the generators of SU(3) group. It turns out that this approach provides a well defined selection rule to give different Hamitonians for each configurations. The lambda and vee type configurations are exactly solved with different initial conditions while taking the ...

Shepel, Michael (U.S. Army Biological Laboratories, Fort Detrick, Frederick, Md.) and Maxwell R. Klugerman. Effect of adjuvants on antibody response of rabbits inoculated with Venezuelan equine encephalomyelitis virus. J. Bacteriol. 85:1150-1155. 1963.-Hemagglutination-inhibition, neutralization, and complement-fixation tests were performed on sera of rabbits inoculated with Venezuelan equine e...