Using the notion of “belongingness ($epsilon$)” and “quasi-coincidence (q)” of fuzzy points with fuzzy sets, we introduce the concept of an ($ alpha, beta$)- fuzzyHv-ideal of an Hv-ring, where , are any two of {$epsilon$, q,$epsilon$ $vee$ q, $epsilon$ $wedge$ q} with $ alpha$ $neq$ $epsilon$ $wedge$ q. Since the concept of ($epsilon$, $epsilon$ $vee$ q)-fuzzy Hv-ideals is an important and ...

Toxin-antitoxin (TA) systems are small genetic elements found in the majority of prokaryotes. They encode toxin proteins that interfere with vital cellular functions and are counteracted by antitoxins. Dependent on the chemical nature of the antitoxins (protein or RNA) and how they control the activity of the toxin, TA systems are currently divided into six different types. Genes comprising the...

There are currently three oral medications approved for the treatment of multiple sclerosis (MS). Two of these medications, Fingolimod, and Teriflunomide, are considered to be anti-inflammatory agents, while dimethyl fumarate (DMF) is thought to trigger a robust antioxidant response, protecting vulnerable cells during an MS attack. We previously proposed that epsilon toxin from the gut bacteriu...

The CCAAT box is one of the conserved motifs found in globin promoters. It binds the CP1 protein. We noticed that the CCAAT-box region of embryonic/fetal, but not adult, globin promoters also contains one or two direct repeats of a short motif analogous to DR-1 binding sites for non-steroid nuclear hormone receptors. We show that a complex previously named NF-E3 binds to these repeats. In trans...

objectives: enterotoxigenic escherichia coli (etec) is one of the most common agents of diarrhea among other bacterial agents. designing and producing vaccine against these bacteria is one of the major purposes of world health organization (who). due to presence of diverse clones of etec strains in the world, the use of global vaccines for etec infection is controversial. b subunit of heat labi...

In the human epsilon-globin gene locus, the HS2 enhancer in the Locus Control Region regulates transcription of the embryonic epsilon-globin gene located over 10 kb away. The mechanism of long-range HS2 enhancer function was not fully established. Here we show that the HS2 enhancer complex containing the enhancer DNA together with RNA polymerase II (pol II) and TBP tracks along the intervening ...

The muscular content of the mRNAs encoding the five subunits of the nicotonic acetylcholine receptor was measured during postnatal development in the rat. Subunit specific mRNAs show differential regulation. The levels of the alpha-, gamma- and delta-subunit specific mRNAs decrease steadily after birth, while the beta- and epsilon-subunit mRNAs increase transiently and then decrease. The adult ...

STUDY OBJECTIVE Age, family history of dementia and the epsilon 4 allele of the apolipoprotein E gene have been associated with Alzheimer's disease (AD). Considering the strength of APOE-epsilon 4 as a genetic risk factor for AD, this factor might explain a large part of the association between AD and a family history of dementia. Therefore, in the general population, a higher frequency of deme...

background and objectives: methicillin resistant staphylococcus aureus (mrsa) strains are divided into community associated (ca-) and hospital associated (ha-) mrsa. these strains vary in antimicrobial resistance and pathogenicity. s. aureus is one of the most common microorganisms in ocular infections. this study was aimed to determine antimicrobial resistance patterns and genetic characterist...

the aim of this paper is to introduce the notions of ($epsilon, epsilon vee q$)-fuzzy p-ideals, ($epsilon, epsilon vee q$)-fuzzy q-ideals and ($epsilon, epsilon vee q$)-fuzzy a-ideals in bcialgebras and to investigate some of their properties. several characterizationtheorems for these generalized fuzzy ideals are proved and the relationshipamong these generalized fuzzy ideals of bci-algebras i...