Abstract The goal of this research was to investigate the ontogenic path followed by somatic embryo from oil palm ( Elaeis guineensis jacq.) with in vitro culture and characterize shoot explants. Explant were injected into a medium for induction calluses, histological analysis perfomed on embryogenic callus embryo. Embryogenic nodular structure still proliferate because cells are meristematic v...

The pathophysiology of psoriasis, an autoimmune skin disorder, that affects approximately 3% the population worldwide, is incompletely understood, despite advanced knowledge. In this study, we investigated role and contribution mTOR signaling in myeloid lineage cells regulating pathogenesis systemic inflammation associated with psoriasis. We first established a genetic mouse model which was spe...

The skin has a pronounced ability to adapt physical changes in the environment by exhibiting plasticity at cellular level. Transient mechanical deformations applied are accommodated without permanent tissue structure. However, sustained stress induces long-lasting alterations skin, which mediated shifts keratinocyte activity. To elucidate mechanism of epidermal stem cell plasticity, we implemen...

The epidermis of clinically normal-appearing human skin harbors a phenotypically heterogeneous population of T lymphocytes (TCs), the majority of which are CD2+/CD3+/CD5+ "memory" cells, but in an unactivated state, and express the TCR-alpha/beta. In contrast to murine skin, only a very minor subpopulation of CD3+ cells in the human epidermis bears the TCR-gamma/delta. Epidermal TCs primarily a...

the body and the environment. The main epidermal cell type is an epithelial cell, the keratinocyte.The major structures of the epidermis are the interfollicular epidermis (IFE), hair follicles (HFs), sweat glands, and sebaceous glands (SGs). In human epidermis, the sweat glands are present in both hair-bearing and hairless regions, whereas in mouse epidermis, the sweat glands are restricted to ...

Based on gene expression patterns, breast cancers can be divided into subtypes that closely resemble various developmental stages of normal mammary epithelial cells (MECs). Thus, understanding molecular mechanisms of MEC development is expected to provide critical insights into initiation and progression of breast cancer. Epidermal growth factor receptor (EGFR) and its ligands play essential ro...

The concept of celebrities has shaped societies throughout history. This work addresses the problem of celebrity identification from social media interactions. “Celebritiness” is a characteristic assigned to persons that are initially based on specific achievements or lineage. However, celebritiness often transcends achievements and gets attached to the person itself, causing them to capture po...

objective(s):from the ancient era, emergence of agriculture in the connecting region of mesopotamia and the iranian plateau at the foothills of the zagros mountains, made iranian gene pool as an important source of populating the region. it has differentiated the population spread and different language groups. in order to trace the maternal genetic affinity between iranians and other populatio...

Fish epidermal mucus contains innate immune components, secreted by globlet cells that provide the primary defence against different pathogenic microbes and act as a barrier between fish and its immediate niche. The major function of mucus includes entrapment and sloughing of microbes. The mucus also contains many factors such as antimicrobial peptides (AMPs), lysozymes, lectins, proteases, etc...

Sulfated polysaccharides have shown promising effects on wound healing processes along with many other biological activities. The sulfated polysaccharides extracted from two algae species habitats in Persian Gulf were studied in vivo for their effects on collagen formation and epidermal regeneration. The polysaccharides were purified from aqueous extracts of P. tetrastromatica and P. boergeseni...