Three cases of neutropenic enterocolitis are described. This unusual condition occurs almost exclusively in neutropenic patients and has a fulminating course which is almost invariably fatal without surgical intervention. The lesion is centered on the caecum and hitherto its pathogenesis has been unclear, partly because most studies have been performed on material obtained at necropsy. In these...

Neutropenia is a common toxicity of systemic cytotoxic therapy. Neutropenic enterocolitis (NE) is a rare occurrence but can be fatal, subsequent to neutropenia. The exact incidence and frequency is difficult to establish, but is usually underestimated. It is often missed but has recently been appreciated with increasing frequency in solid tumours. NE was initially reported with taxenes but now ...

The clinical presentation of appendicitis in the newborn is nonspecific. The diagnosis was always made after surgical exploration for acute abdominal findings mimicking necrotizing enterocolitis. We report the case of acute appendicitis in a newborn diagnosed intraoperatively after neonatal occlusion symptoms.

Bacillus cereus is increasingly being acknowledged as a serious bacterial pathogen in immunosuppressed hosts. We report a case of fatal B. cereus sepsis in a patient with newly diagnosed acute leukemia following resolving neutropenic enterocolitis. Gastrointestinal complaints are common during induction chemotherapy, yet some antimicrobial coverage suitable for generalized neutropenia is not op...

Objectives This is a protocol for Cochrane Review (intervention). The objectives are as follows: To evaluate the effectiveness of enteral supplementation with prebiotic oligosaccharides on risk necrotising enterocolitis, and associated morbidity mortality, in very preterm or low birth weight infants.

Lay Summary Necrotizing enterocolitis remains one of the most common gastrointestinal emergencies in neonates. Neonates admitted to a resource-restricted neonatal intensive care unit with presumptive diagnosis advanced NEC were reviewed. We able identify risk factors associated higher chance death or poor neurodevelopmental outcomes. Our outcomes are comparable international literature.

Necrotizing enterocolitis (NEC) is among the most common and devastating diseases that primarily afflicts preterm infants in neonatal intensive care units (NICU) (1). Despite recent advances in neonatal care, the incidence of necrotizing enterocolitis and the associated morbidity and mortality have remained unchanged because of the improved survival for smaller, more premature infants (2). Both...

The clinical presentation, diagnostic features, therapeutic measures, and results of treatment of 29 infants with the firmly established diagnosis of necrotizing enterocolitis are reviewed. A cohort of control patients are studied in an attempt to identify risk factors which may predispose infants to develop this serious complication of the newborn period. The incidence of necrotizing enterocol...

Necrotising enterocolitis (NEC) is an gastro-intestinal emergency occurring almost solely in preterm, low birth weight infants. Mortality, morbidity and the complication rate are high. An increase in NEC at the Groote Schuur Hospital nursery in 2008 prompted a change of practice, resulting in a significant decrease in the condition.