Canine distemper (CD) caused by canine virus (CDV) is considered a highly contagious and acutely febrile disease in various animals around the world. Endoplasmic reticulum-associated protein degradation (ERAD) an important biological effect induced endoplasmic reticulum (ER) stress (ERS) for of unfolded/misfolded proteins ER cells. CDV H glycoprotein translocated into post-translational modific...

Significance Endoplasmic reticulum (ER) stress is a condition triggered by adverse environmental conditions, which in plants include extreme heat, pathogen infection, and drought. These stresses can have devastating effect on agricultural productivity, the appropriate responses of to are therefore critical. Autophagy macromolecular degradation pathway that activated response stress, including E...

Background: Photoreceptors undergo degeneration when phototransduction is impaired. Results: The endoplasmic reticulum stress markers and processing of the associated caspases are elevated in retinas with cone photoreceptor CNG channel deficiency. Conclusion: The endoplasmic reticulum stressassociated apoptotic pathways play a crucial role in cone degeneration. Significance: Understanding of th...

The endoplasmic reticulum (ER) is the major site of calcium storage and protein folding. It has a unique oxidizing-folding environment due to the predominant disulfide bond formation during the process of protein folding. Alterations in the oxidative environment of the ER and also intra-ER Ca2+ cause the production of ER stress-induced reactive oxygen species (ROS). Protein disulfide isomerases...

Instituto de Bioquímica Vegetal y Fotosíntesis, Consejo Superior de Investigaciones Científicas-Universidad de Sevilla, 41092 Seville, Spain (M.P.-M., J.L.C.); and Centre National de la Recherche Scientifique (M.E.P.-P.; S.D.L.) and Sorbonne Universités, Université Pierre et Marie Curie, University of Paris 06 (M.E.P.-P.; S.D.L.), Unité Mixte de Recherche 8226, Laboratoire de Biologie Moléculai...