BACKGROUND The prevalence and risk factors for endometriosis may differ according to diagnosis methodologies, such as study populations and diagnostic accuracy. We examined risk profiles in imaging-diagnosed endometriosis with and without surgical confirmation in a large population of Japanese women, as well as the differences in risk profiles of endometriosis based on history of infertility. ...

Endometriosis is one of the most common gynecological diseases and affects ~10% of women in reproductive age. The most common clinical signs of endometriosis are menstrual irregularities, chronic pelvic pain (CPP), dysmenorrhea, dyspareunia and infertility. Symptoms of endometriosis often affect psychological and social functioning of patients. For this reason, endometriosis is considered as a ...

Abstract Study question Do gut microbial composition and functionality differ between women with without endometriosis? Summary answer Gut microbiome diversity (species pathways) were not significantly different endometriosis. What is known already Endometriosis, defined as the presence of endometrial-like tissue outside uterus, one most common female reproductive disorders. Although theories p...

THE AIM OF THE STUDY The aim of the study was to investigate the serum pro-inflammatory cytokine profile in patients with diagnosed endometriosis. MATERIAL AND METHODS The study included 160 women, who were divided in two study groups (Group I - endometriosis; Group 2 - healthy). We evaluated the serum levels of interleukin (IL)-1β, IL-5, IL-6, IL-7, and IL-12, and of tumour necrosis factor α...

The aim of the present study was to investigate whether endometriosis and cancer share common molecular characteristics. Tissue samples were collected prospectively during diagnostic laparoscopy of patients with primary infertility. Using high-density oligonucleotide microarrays, (Affymetrix Gene Chip HG-U133 Set) the genome-wide gene expression profile of advanced ovarian endometriosis was ana...

background: to evaluate the possible association between phthalate esters (pes) and the occurrence of endometriosis. blood samples were collected from 99 infertile women with endometriosis (study group); 135 age-matched women without endometriosis (control group) but with infertility related to tubal defects, fibroids, polycystic ovaries, idiopathic infertility and pelvic inflammatory diseases ...

OBJECTIVE To generate and validate symptom-based models to predict endometriosis among symptomatic women prior to undergoing their first laparoscopy. DESIGN Prospective, observational, two-phase study, in which women completed a 25-item questionnaire prior to surgery. SETTING Nineteen hospitals in 13 countries. PATIENT(S) Symptomatic women (n = 1,396) scheduled for laparoscopy without a p...

BACKGROUND Endometriosis, classified as the presence of endometrial cells in ectopic sites, is a debilitating disease causing pain and infertility in approximately 10% of women of reproductive age. It is associated with the aberrant expression of extracellular matrix (ECM) components and their receptors, integrins. METHODS We analysed the expression of integrins in stromal cells derived from ...

background the 12-item general health (ghq-12) questionnaire is one of the most commonly used instruments in screening studies on mental health. objectives the current study aimed to examine the factor structure of the ghq-12 questionnaire among the students in iran. materials and methods it was a cross-sectional study in which 428 university students were recruited and completed the ghq-12. re...