Embryo implantation represents the most critical step of the reproductive process in many species. Inadequate uterine receptivity is responsible for approximately two-thirds of implantation failures. The cell adhesion molecule (CAM) such as integrins, cadherins, selectins and immunoglobulins intervene to ensure adhesiveness between the embryo and the endometrium. Some recent studies indicate th...

Background Endometriosis is the presence of endometrial tissue outside of the uterine cavity and is the most common gynecologic disorder in women of reproductive age. We have preliminary evidence that in the presence of a 3-dimensional (3-D) fibrin matrix, human endometrial glands, stroma, and neovascularization can develop in vitro, mimicking the earliest stages of endometriosis. The aim of th...

mesenchymal stem cells can be obtained from deferent tissues like adipose tissue, umbilical cord, placenta, skin, bone marrow, etc. these cells have regulatory effects on all types of immune cells such as dendritic cell, natural killers and lymphocytes. mesenchymal stem cells induce inhibitory phenotypes of antigen presenting cells (apcs) following their activity. they also change t cells pheno...

purpose : our aim was to isolate mesenchymal stem cells (mscs) from mouse umbilical cord and culture them with vitreous body to investigate their capacity to differentiate into lens fiber cells, crystallins are expressed. methods : wharton's jelly is the appropriate source of mscs. after isolation, the cells were cultured and alkaline phosphatase detection kit was used for staining undiffe...

background: mesenchymal stem cells (mscs) are undifferentiated cells that can differentiate and divide to other cell types. transplantation of these cells to the different organs is used for curing various diseases. objective: the aim of this research was whether mscs transplantation could treat the sterile testes. materials and methods: in this experimental study, donor mscs were isolated from...

ex vivo expansion of human umbilical cord blood cells (hucbc) is explored by several investigators to enhance the repopulating potential of hucbc. the proliferation and expansion of human hematopoietic stem cells (hsc) in ex vivo culture was examined with the goal of generating a suitable clinical protocol for expanding hsc for patient transplantation. using primary human mesenchymal stem cells...

objectives: the study of erythropoiesis needs to develop the methods for erythroid progenitor cells (epcs) culture using stem cell potency to differentiate into variety of hematopoietic cells lineages. in this study, we induced differentiation of cord blood stem cells into erythroid progenitor cells in a semisolid culture media. materials and methods: cord blood mononuclear cells were isolate...