Current studies try to demonstrate a tight correlation between the endocrine and the neuropsychiatric physiopathology by a total different approach of the common pathology supporting an essential link between the neuro-hormonal mechanisms triggering the disorders from the depressive sphere and those from the scope of the crude hypothyroidism and of the serious forms. The medicines interaction b...

Autoimmune polyglandular syndrome (APS) type I is a disorder that consists of three primary diseases: hypoparathyroidism (HPT), adrenocortical insufficiency (ACI) and chronic mucocutaneous candidiasis. Several other disorders may be associated. The diagnosis of APS type I was made in a 16-year-old patient with HPT, Hashimato's thyroiditis and ACI in our department. She has been observed for mor...

Endocrine hypertension belongs to the group of secondary forms of hypertension and mostly is caused by disorders of the adrenal gland. There are also nonadrenal endocrine conditions that can lead to hypertension secondary to hormonal imbalance and this chapter reviews how to best identify patients with and test for such disorders. For complete coverage of all related areas of Endocrinology, ple...

Aims Mitochondrial diseases are a heterogeneous group of genetic disorders that result from dysfunction of the respiratory chain. The endocrine disorders such as diabetes mellitus, hypoparathyroidism, hypothyroidism and growth hormone deficiency have been described in patients with mitochondrial DNA mutations. Among these, patients with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stro...

Next-generation sequencing (NGS) and array-based comparative genomic hybridization (array CGH) have enabled us to perform high-throughput mutation screening and genome-wide copy number analysis, respectively. These methods can be used for molecular diagnosis of pediatric endocrine disorders. NGS has determined the frequency and phenotypic variation of mutations in several disease-associated gen...

What a long way since 1908, when Laignel Lavastine laid out the first concepts of endocrinological psychiatry in Dijon at a psychiatric congress entitled ‘‘Des troubles psychiques par perturbations des glandes à sécrétion interne’’ (mental disorders due to disturbances of endocrine glands). During the last third of the 20th century, the interest of psychiatrists and researchers shifted graduall...

Hair loss may accompany several endocrine disorders, including hypopituitarism, hypothyreosis, hyperthyreosis, hypoparathyroidism, diabetes mellitus, growth hormone deficiency, hyperprolactinaemia, polycystic ovary syndrome, SAHA syndrome, congenital adrenal hyperplasia, Cushing syndrome, or virilising tumours. Most patients with endocrine disorders present with diffuse non-scarring alopecia, s...