Background: Tick-Borne Relapsing Fever (TBRF) was once a major world-wide epidemic disease and was an endemic disease like malaria in Sengerema district, close to Lake Victoria, Tanzania. Our aim was to study the incidence and fatality of TBRF over the past 60 years. Methods: From 1962 to 2015, we analyzed the annual reports, number of admissions, blood smears of patients with fever from Borrel...

BACKGROUND In Africa, relapsing fever borreliae are neglected arthropod-borne pathogens causing mild to deadly septicemia and miscarriage. The closely related Borrelia crocidurae, Borrelia duttonii, Borrelia recurrentis and Borrelia hispanica are rarely diagnosed at the species level, hampering refined epidemiological and clinical knowledge of the relapsing fevers. It would be hugely beneficial...

Rodents, both commensal and wild, serve as reservoirs for a variety of diseases in nature communicable to man. Forty-six percent of the 30 human plague cases in the past two decades in California are associated with campgrounds and public use recreational sites. In addition, human cases of tularemia, giardiasis, relapsing fever, Rocky Mountain spotted fever, Colorado tick fever, and Lyme diseas...

A hallmark of acute relapsing fever borreliosis is severe bacteremia. Some Borrelia species, such as B. duttonii and B. crocidurae, associate with erythrocytes and induce aggregation recognized as erythrocyte rosetting. Erythrocyte rosettes contribute to disease severity by increased tissue invasiveness (such as invasion of CNS and encephalitis), hemorrhaging, and reduced blood flow in affected...

In 2017, two cases of dengue fever were imported from Hurghada, Egypt, where dengue fever was not considered endemic, to Moscow. These cases show how emergence of dengue fever in popular resort regions on the coast of the Red Sea can spread infection to countries where it is not endemic.

Relapsing fever spirochetes are tick- and louse-borne pathogens that primarily afflict those in impoverished countries. Historically the pathogens have had a significant impact on public health, yet currently they are often overlooked because of the nonspecific display of disease. In this review, we discuss aspects of relapsing fever (RF) spirochete pathogenesis including the: (1) clinical mani...

Analysis of the fatty acid methyl esters (FAMEs) of bacteria is a commonly used chemotaxonomic technique. Application of this methodology to spirochaetes associated with Lyme borreliosis revealed distinct clusters corresponding to three genetically distinguished groups: Borrelia burgdorferi sensu stricto, B. garinii, and the VS461 group. However, B. garinii formed a common group with B. hermsii...

Yellow fever is a potentially fatal viral hemorrhagic fever. Although an effective vaccine (yellow fever 17D) has been available since the late 1930s, utilization is incomplete in many areas, particularly in Africa, with the result that yellow fever epidemics still occur. Official reports of yellow fever between 1965 and 2004 in South America and Africa total over 33,000 cases. In West Africa, ...

cott MJ. Fatal spirochetosis due to a relapsing fever−like Borrelia sp. in a northern spotted owl. of tick-borne relapsing fever caused by Borrelia hermsii. al. Variable tick protein in two genomic groups of the relapsing fever spirochete Borrelia hermsii in western North Ameri-ca. To the Editor: Documentation of possible tuberculosis (TB) in goats in Nigeria was reported by Ojo (1) on the basi...