Leprosy control programs would benefit expressively from an easy method to estimate disease prevalence and to assess the effect of leprosy control measures on disease prevalence. Determination of the seroprevalence of antibodies to PGL-I through school children surveys might be a useful indicator of leprosy prevalence at the district level. To investigate whether seropositivity rates could be r...

OBJECTIVES Trimethoprim/sulfamethoxazole is commonly used to treat melioidosis. Antimicrobial susceptibility testing using the disc diffusion method is commonly used in melioidosis-endemic areas, but may overestimate resistance to trimethoprim/sulfamethoxazole. PATIENTS AND METHODS We performed disc diffusion and Etest on isolates from the first positive culture for all patients presenting to...

BACKGROUND Deficiencies of iodine, iron, and vitamin A are the 3 most common micronutrient deficiencies in developing countries, although control programs, when properly implemented, can be effective. OBJECTIVE We investigated these deficiencies and their possible interaction in preschool children in the southern Blue Nile area of Sudan. DESIGN Goiter, signs of vitamin A deficiency, and bio...

BACKGROUND Endemic goiter is present in most parts of Iran. Iron deficiency adversely affects the physiology of thyroid. The initial steps of thyroid hormone synthesis are catalyzed by thyroperoxidases and are dependent on iron. In many developing countries, children are at high risk of both goiter and iron deficiency anemia. In addition, iron deficiency may alter central nervous system control...

BACKGROUND Iodine deficiency produces the spectrum of iodine deficiency disorders (IDDs) including endemic goiter, hypothyroidism, cretinism and congenital anomalies. Other factors, including goitrogens and micronutrient deficiencies may influence the prevalence and severity of IDDs and response to iodine supplementation. An association between zinc and goiter has previously been reported. ME...

1 Goiter or goiter (Latin gutteria, struma), is an enlargement (1656) . Massive thyroid enlargement is more common in of the thyroid gland, which can lead to a swelling of the endemic areas where the commonest cause is iodine neck has been a recognized medical condition since 2700 deficiency. Cosmesis, dysponea, dysphagia or voice B.C. Interestingly, the thyroid gland itself was not changes are...

Hainan is a single bancroftian filariasis endemic province where filariasis is prevalent in all 18 cities and counties. A program to control filariasis was started in 1953. The strategy of eliminating infection sources has been adopted as the principal intervention measure in filariasis control. Over 30 years, the sustained effort throughout the province reached the point of basic elimination o...

The use of thyroid-depressant agents in the control of hyperthyroidism has raised questions concerning their relationship to other goitrogens and their mode of action. Other problems have been encountered as well, particularly with respect to toxic reactions, the effect of preliminary iodine administraton, and the control of the hypothyroid state which may result. The information available on t...

In the fall of 1991, the incidence of goiter was determined in I07X male and female school children in Kermanshah city. The study was considered from two view points i.e., clinical examinations and measurements of levels of iodine excreted in urine, and was performed in three age groups: 7-11 years of age, 12-15 years of age and 16-18 years of age. Clinical examination showed 16.5% occurre...