Introduction The broad definition of the term “encephalitis,” that is, inflammation of the brain, necessitates acknowledgment of the enormous inclusivity of the topic. The most common interpretation of the term implies a direct invasion of the brain by an infectious pathogen, most commonly, viral, fungal, or parasitic. The topic also includes examples of meningitis mediated by bacteria or other...

Correspondence to: Professor P G E Kennedy, Department of Neurology, University of Glasgow, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF, UK; p.g.kennedy@ clinmed.gla.ac.uk _________________________ E ncephalitis refers to an acute, usually diffuse, inflammatory process affecting the brain. While meningitis is primarily an infection of the meninges, a combined ...

We reported a 16-year-old girl, with diffuse vesicular rashes all over the body, presented to emergency department altered mental status, irritability, persistent fever and one episode of generalized tonic-clonic seizure. After thorough evaluation investigations, case was varicella zoster-associated encephalitis in an unvaccinated patient. Appropriate treatment initiated, patient then shifted c...

Encephalitis usually refers to brain inflammation of various possible causes, including viral infections. Overall, viruses represent the most common cause of encephalitis in humans. The U.S. Center for Disease Control and Prevention (CDC) estimates an annual incidence of usually between 150 and 3000 new cases per year of Arboviral encephalitis in the United States (http://www.cdc.gov/). Althoug...

Three cases of herpes encephalitis are described. A definite diagnosis was established and all patients made a good recovery without specific antiviral chemotherapy. These reports are representative of those forms of herpes encephalitis with a good prognosis. It is suggested that the introduction of rapid non-invasive procedures will indicate a higher incidence of herpes encephalitis than is pr...

The incidence of herpes simplex virus (HSV) encephalitis exceeds that of other forms of acute viral encephalitis. It is widely acknowledged that the use of PCR amplification for the detection of HSV DNA in cerebrospinal fluid (CSF) has increased our diagnostic sensitivity for this illness, leading to the diagnosis of HSV encephalitis in a wide range of clinical presentations. It is important to...

Herpes simplex virus Type 1 (HSV-1) is a human neurotropic virus causing encephalitis, corneal blindness or several peripheral nervous system disorders. Herpes Simplex encephalitis (HSE) is the most devastating clinical syndrome with severe morbidity and mortality. Hydrocephalus associated with viral meningoencephalitis is an extremely rare entity with only few documented cases, predominantly d...

Hypersalivation is one of the intractable symptoms of anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis. While anticholinergic medications partially improve the hypersalivation, they can aggravate the autonomic dysfunctions associated with anti-NMDAR encephalitis. Thus, we investigated the efficacy and safety of botulinum toxin type A injection on hypersalivation refractory to anticholine...

We describe a case of chronic atypical herpes simplex type 2 encephalitis in an immunocompromised 68 year old man presenting with headache and cognitive changes without focal neurological or MRI findings. To our knowledge this is the first described case of herpes simplex encephalitis associated with normal MRI brain imaging and non-focal neurological examination. This further expands the range...

We measured the performance of exposure screening questions to identify Nipah virus encephalitis in hospitalized encephalitis patients during the 2012-13 Nipah virus season in Bangladesh. The sensitivity (93%), specificity (82%), positive predictive value (37%), and negative predictive value (99%) results suggested that screening questions could more quickly identify persons with Nipah virus en...