The problem of 'competition' between neurones innervating the same target can be studied in simple neural systems such as the central nervous system of the leech and the lobster neuromuscular junction. Intracellular injection of pronase to kill selectively a single neurone shows that, in the leech, removal of one neurone is a sufficient signal to produce compensatory changes. After removal of a...

The World Health Assembly should establish a target date for measles eradication based on continued progress toward existing mortality reduction goals. We have a safe, effective, and inexpensive vaccine; a proven elimination strategy; high country demand; and an effective global partnership. Since it was founded in 2001, the Measles Initiative has supported the vaccination of >900 million child...

Myanmar has one of the largest malaria burdens in the Greater Background: Mekong Subregion (GMS). Throughout the GMS, Plasmodium falciparum parasites are increasingly resistant to artemisinin combination therapies. Given that there are no current alternative treatment therapies, one proposed solution to the threat of untreatable malaria is to eliminate the parasite P. falciparum from the region...

International rabies networks have been formed in many of the canine-rabies endemic regions around the world to create unified and directed regional approaches towards elimination. The aim of the first sub-regional Eastern Africa rabies network meeting, which included Kenya, Ethiopia, Tanzania, Rwanda, and Uganda, was to discuss how individual country strategies could be coordinated to address ...

The place of leprosy in the control–elimination–eradica-tion spectrum Editor – I would like to expand on Lockwood & Suneetha's reflections on the leprosy elimination campaign (1), and in particular their statement that " leprosy is perhaps more appropriately classed as a chronic stable disease rather than as an acute infectious disease responsive to elimination strategies " , by using the contr...

In the context of mod-Gaussian convergence, as defined previously in our work with J. Jacod, we obtain asymptotic formulas and lower bounds for local probabilities for a sequence of random vectors which are approximately Gaussian in this sense, with increasing covariance matrix. This is motivated by the conjecture concerning the density of the set of values of the Riemann zeta function on the c...

Some positivity conjectures are made generalizing known results for Gaussian posets. For a sequence of non-negative integers ~ a = (a 1 ; a 2 ; ; a n), and a non-negative integer m, MacMahon 1, p. 137] considered the rational function of q,

V r /2 t,p/2 is a scaled version of Gaussian measure with r p if 1 < p < 2 and r p ′ if 2 < p < ∞ with 1/p 1/p′ 1. Conversely if F is a holomorphic function which is in a “slightly” smaller space, namely L C, V r/2 t,p/2 , then it is shown that there is a function f ∈ L R, ρ such that e−tHf F. However, a single necessary and sufficient condition is obtained for the image of L2 R, ρp/2 under e−t...