CARDIAC ELECTROPHYSIOLOGY CLINICS www.cardiacEP.theclinics.com Consulting Editors RANJAN K. THAKUR ANDREA NATALE June 2021 • Volume 13 Number 2

CARDIAC ELECTROPHYSIOLOGY CLINICS www.cardiacEP.theclinics.com Consulting Editors RANJAN K. THAKUR ANDREA NATALE November 2021 • Volume 13 Number 4

Recently, significant achievements have beenmade in cardiac electrophysiology research, including Ca regulatory pathways, membrane ion channel-related intracellular signaling, and electrical remodeling in cardiomyopathies. The rapid progress in the basic research has led to applications of numerous new methods and strategies to clinical diagnoses and treatments. The efficacy of antiarrhythmic p...

In all kingdoms of life, pentameric ligand-gated ion channels mediate electrical activity in response to chemical stimuli including pH, neurotransmitters, alcohols, and a wide range pharmacological agents. Recent biochemical structural studies this family receptors have identified putative binding sites for various agonists modulators, but leave open questions as the mechanisms coupling between...

CARDIAC ELECTROPHYSIOLOGY CLINICS www.cardiacEP.theclinics.com Consulting Editors JORDAN M. PRUTKIN EMILY P. ZEITLER March 2023 • Volume 15 Number 1

Visual electrophysiology is widely used in clinical ophthalmology. It is also of significant value in the objective assessment of visual function in adult and pediatric cataract patients and for the diagnosis of and research on retinal and visual pathway diseases. This article systematically reviews visual electrophysiology techniques, their applications in the diagnosis and treatment of adult ...

This work introduces a novel, unconditionally stable and fully coupled finite element method for the bidomain system of equations of cardiac electrophysiology. The transmembrane potential Φ(i)-Φ(e) and the extracellular potential Φ(e) are treated as independent variables. To this end, the respective reaction-diffusion equations are recast into weak forms via a conventional isoparametric Galerki...

Intracardiac pacemaker and defibrillator implantations were initially described a half century and a quarter century ago, respectively.1,2 Originally conceived as devices for the treatment of symptomatic bradycardia and sustained ventricular tachyarrhythmias, these therapies have subsequently been applied to the management of an increasing host of arrhythmia and other indications, including the...

INTRODUCTION The "Experimental Data and Geometric Analysis Repository", or EDGAR is an Internet-based archive of curated data that are freely distributed to the international research community for the application and validation of electrocardiographic imaging (ECGI) techniques. The EDGAR project is a collaborative effort by the Consortium for ECG Imaging (CEI, ecg-imaging.org), and focused on ...

Electrophysiology, which is the study of electrical properties biological tissues and cells, has become indispensable in modern clinical research, diagnostics, disease monitoring therapeutics. In this paper we present a brief history discipline how integrated circuit design shaped electrophysiology last few decades. We will discuss biopotential amplifier evolved from classical three-opamp archi...