Iontophoresis is one of the skin permeation enhancement methods involving the transport of drugs through the skin under the effect of electrical current. The effect of molecular charge on the iontophoretic permeation of drugs has not been completely understood yet. Therefore the effect of passive and iontophoretic permeation of L-phenylalanine at pH 3.6 (positive charge) and pH 8 (negative ch...

Dynamic characteristics of electroosmosis of a typical non-Newtonian liquid in a rectangular microchannel are investigated by using numerical simulations. The non-Newtonian behavior of liquids is assumed to obey the famous power-law model and then the mathematical model is solved numerically by using the finite element method. The results indicate that the non-Newtonian effect produces some not...

DOI: 10.1002/elps.202000086 The cover picture shows the determination of four alkyl sulfate (AS) surfactants (C14, C12, C10, and C8) by capillary electrophoresis (CE) after preconcentration simultaneous adsorption AS on Al2O3 surface. EOF electroosmotic flow (EOF) at high pH pushes move to contactless conductivity detector (C4D). electropherograms show separation in order C14, C8.

We present experimental investigations of electroosmotic pumping using porous borosilicate glass and various low ion density liquids. The orking liquids were deionized water, deuterium oxide (heavy water), methanol, acetone, acetonitrile and a 1 mM sodium borate buffer as a ontrol. We measured ionic conductivity and, as a useful comparative reference, the zeta potential generated by these liqui...

A simple coating procedure employing a sol-gel process to modify the inner surface of a bare fused-silica capillary with a positively charged quaternary ammonium group is established. Scanning electron microscopic studies reveal that a smooth coating with 1 to approximately 2 microm thickness can be obtained at optimized coating conditions. With 40 mM citrate as a running electrolyte, the plot ...

We present dissipative particle (DPD) simulations of electrolyte flow in nanochannels for varying salt concentration and surface slip conditions. First, a method is presented by which the slip length δ Β at the channel boundaries can be tuned systematically from negative to infinity by introducing suitable wall-fluid friction forces. Using this method, we study electroosmotic flow (EOF) in nano...