Job shop scheduling (JSS) problems are optimisation problems that have been studied extensively due to their computational complexity and application in manufacturing systems. This paper focuses on a dynamic JSS problem to minimise the total weighted tardiness. In dynamic JSS, jobs’ attributes are only revealed after they arrive at the shop floor. Dispatching rule heuristics are prominent appro...

Type 2 diabetes is characterized by increased insulin resistance and impaired insulin secretion. Type 2 diabetes is also associated with low-grade inflammation and increased levels of proinflammatory cytokines such as TNF-α. TNF-α has been shown to impair peripheral insulin signaling in vitro and in vivo. However, it is unclear whether TNF-α may also affect endogenous glucose production (EGP) d...

We study Web sessions clustering in order to find groups of similar sessions and discover user access patterns on a Web site. We extend the general page concept presented in (Fu, Sandhu and Shih 2000) by including partial document names and dynamic pages, and use an extended general page (EGP) to represent many individual page URLs sharing the same EGP. We present two extensions of a hierarchic...

To investigate the role of β-adrenergic mechanisms in the counterregulatory response of the liver and kidney to hypoglycemia, we studied 10 dogs before and after a 2-h constant infusion of insulin (4 mU ⋅ kg-1 ⋅ min-1) either without ( n = 4) or with (8 μg/min, n = 6) propranolol and variable dextrose to maintain hypoglycemia, 7 days after surgical placement of sampling catheters in left renal ...

Long-term reduced hypothalamic estrogen signaling leads to increased food intake and decreased locomotor activity and energy expenditure, and ultimately results in obesity and insulin resistance. In the current study, we aimed to determine the acute obesity-independent effects of hypothalamic estrogen signaling on glucose metabolism. We studied endogenous glucose production (EGP) and insulin se...

In the present study the hypothesis tested was that prior exercise may blunt counterregulatory responses to subsequent hypoglycemia. Healthy subjects [15 females (f)/15 males (m), age 27 +/- 1 yr, body mass index 22 +/- 1 kg/m(2), hemoglobin A(Ic) 5.6 +/- 0.5%] were studied during 2-day experiments. Day 1 involved either 90-min morning and afternoon cycle exercise at 50% maximal O2 uptake (VO2(...

Background: Growth hormone (GH) is known to affect insulin and glucose metabolism.  Blocking its effects in acromegalic patients improves diabetes and glucose metabolism. We aimed to determine the effect of pegvisomant, a GH receptor antagonist, on insulin resistance, endogenous glucose production (EGP) and lipolysis in insulin resistant non-diabetic men.  Methods: Four men between the ages of ...

In project scheduling studies, to the best of our knowledge, hyper-heuristic collaborative is first-time applied with random activity durations. A based ensemble genetic programming (HH-EGP) method proposed for solving stochastic resource constrained problem (SRCPSP) by evolving an priority rules (PRs). The approach features (1) integrating critical path into resource-based policy class generat...

In social stratification research, the most frequently used class schema are based on employment relations (EGP and ESEC). These schemes have been propelled to paradigms for research mobility educational inequalities applied in cross-national both genders. Using European Working Conditions Survey, we examine their criterion construct validity across 31 countries We investigate whether classes w...

Therapists and patients enjoy and benefit from interventions that use electronic games (EG) in health care and mental health settings, with a variety of diagnoses and therapeutic goals. We reviewed the use of electronic games designed specifically for a therapeutic purpose, electronic games for psychotherapy (EGP), also called serious games, and commercially produced games used as an adjunct to...