BACKGROUND The convergence of rising health care costs and physician shortages have made health care transformation a priority in many countries resulting in the emergence of new models of care that often involve the extension of the scope of practice for allied health professionals. Physiotherapists in advanced practice/extended scope roles have emerged as key providers in such new models, esp...

BACKGROUND The imminent publication of a randomised controlled trial from the USA that suggests CT screening reduces mortality from lung cancer by more than 20%, may potentially lead to one of the most important developments in lung cancer care. However, there remain important questions about the applicability of the results to the UK and the clinical effectiveness of this intervention, includi...

This study conducts a cost-effectiveness analysis of a childhood universal varicella vaccination program in Brazil. An age and time-dependent dynamic model was developed to estimate the incidence of varicella for 30 years. Assuming a single-dose schedule; vaccine efficacy of 85% and coverage of 80%, the program could prevent 74,422,058 cases and 2905 deaths. It would cost R$ 3,178,396,110 and s...

This study investigated the effectiveness of compensation on behavioral intentions through perceived equity, which is moderated by consumer-service organization relationships. Online survey was conducted to collect data, using hypothetical scenarios manipulating recovery efforts and relationship level conditions. Mediation tests showed that perceived equity fully mediate the effect of compensat...

OBJECTIVE This review assessed the level of evidence and effectiveness of peer support services delivered by individuals in recovery to those with serious mental illnesses or co-occurring mental and substance use disorders. METHODS Authors searched PubMed, PsycINFO, Applied Social Sciences Index and Abstracts, Sociological Abstracts, Social Services Abstracts, Published International Literatu...

OBJECTIVES To review the literature to identify whether, and how, physiotherapists working in extended scope of practice (ESP) engage with patients with inflammatory arthropathies. Measures of effectiveness of ESP were particularly sought. METHODS A comprehensive library database search was conducted to identify English language studies published in full text in peer-reviewed journals during ...

Microglia is a type of glial cell located throughout the central nervous system (CNS), which is sensitive to CNS injury and disease. Responsibility of microglia as the resident macrophage cells for injuries suggests that these cells have the potential to act as diagnostic markers of disease beginning or progression. Function of Microglia is strongly synchronized by the microenvironment of brain...

It is generally accepted that role mining—that is, the discovery of roles through the automatic analysis of data from existing access control systems—must count on business requirements to increase its effectiveness. Indeed, roles elicited without leveraging on business information are unlikely to be intelligible by system administrators. A business-oriented categorization of users and permissi...