This paper has a two-fold purpose: first, to present the signs and symptoms of atrial septal defect and thus outline the findings that help in making the clinical diagnosis, and secondly, to show that correct and early diagnosis is important, because this anomaly gives rise to serious, although frequently obscured, symptoms and disabilities more often than has been generally realized. Clinicall...

Ecker, Phillip M., Chu-Chuan Lin, Jennifer Powers, Brian K. Kobilka, Anne M. Dubin, and Daniel Bernstein. Effect of targeted deletions of !1and !2-adrenergic-receptor subtypes on heart rate variability. Am J Physiol Heart Circ Physiol 290: H192–H199, 2006. First published August 19, 2005; doi:10.1152/ajpheart.00032.2005.— !-Adrenergic receptors (!-ARs) play a major role in regulating heart rate...

Since October 1954 we have been treating major paroxysmal trigeminal neuralgia (tic douloureux) by precise alcoholic injection of the trigeminal root and ganglion (Ecker and Perl, 1958). To reach the ganglion the needle enters the anterior part of the cheek and proceeds through the foramen ovale. With Penman's (1953) radiographic technique we determine the exact relation of the intracranial tip...

Annular pancreas is a rare congenital anomaly in which a ring of pancreatic tissue encircles the secondpart of the duodenum [1]. Here we present the endoscopic findings in two patientswith annular pancreas, including the first endoscopic ultrasound (EUS) video to be published of the condition, illustrating the pancreatic duct coursing around the duodenum. Our first patient was a 70-year-old man...

I t was demonstrated in the preceding paper (1) that incubation of primary isolates of normal human amnion cells with specific rabbit antibody and normal human serum resulted in immune cellular injury as measured by two independent criteria of cytotoxicity. I t was further shown that the factors in normal human serum which were required in addition to specific antibody for production of cytotox...

ince early March 2014, >20,000 probable and suspect addresses considerations for pregnant women with epidemiS cases of Ebola virus disease (EVD) have been reported in Guinea, Sierra Leone, and Liberia, with more than 8000 deaths reported as of Jan. 4, 2015. Although pregnancy data are limited, reports of pregnant women with EVD in this and previous outbreaks describe very high maternal, fetal, ...

Mean curvature flow evolves isometrically immersed base Riemannian manifolds M in the direction of their mean curvature in an ambient manifold M̄ . We consider the classical solutions to the mean curvature flow. If the base manifold M is compact, the short time existence and uniqueness of the mean curvature flow are well-known. For complete noncompact isometrically immersed hypersurfaces M (unif...

1 Fanburg-Smith JC, Michal M, Partanen TA, Alitalo K, Miettinen M. Papillary intralymphatic angioendothelioma (PILA): a report of twelve cases of a distinctive vascular tumor with phenotypic features of lymphatic vessels. Am J Surg Pathol 1999; 23: 1004–1010. 2 McKee PH, Calonje E, Grantner SR, eds. Pathology of the Skin, 3rd edn. Elsevier Mosby, London, 2005: 1829–1830 3 Weedon D. Weedon’s Ski...