Spiradenoma & cylindroma are relatively uncommon sweat gland tumors. These lesions along with trichoepithelioma can co-exist and this gives support to the theory that they are part of the same spectrum and have a similar derivation.They can occur as separate lesions or within a single tumor mass as collision tumors.Here we report a case of a 67 year old female who presented with multiple papulo...

Eccrine poroma is a benign neoplasm thought to originate from the eccrine sweat glands. The majority of eccrine poroma occur on the hairless acral surface, and cases of eccrine poroma on the scalp are rare. Moreover, all these case reports describe only the histopathological, not radiological, features of eccrine poroma. Here, we first report the magnetic resonance (MR) findings in a rare case ...

The predisposition to epithelial neoplasms in nevus sebaceous is well established; most tumors occur in adults and are benign. Hidradenoma is a relatively rare benign tumor of sweat gland origin that can rarely arise within a nevus sebaceous. We present an interesting case of a hidradenoma and sebaceoma arising within a nevus sebaceous and present a literature review of the 2 conditions. Even t...

The junctional complex connecting epithelial cells at their luminal pole consists of a complex of highly specialized structures which provide attachment (5-7) and communication (10) between cells . This junctional complex includes the zonula occludens, the underlying zonula adherens and, at intervals, the subjacent macula adherens or desmosome. Although this complex of fine structures occurs ve...

1. Intra-arterially as well as intradermally administered adrenaline or noradrenaline produces a sweat response. 2. The intensity of the intradermal response is always considerably less than that due to acetylcholine and the threshold of effective concentration is considerably greater than for acetylcholine. The glands also fail to respond to repeated small doses of intradermal catecholamine an...

a case of pleomorphic adenoma in sweat gland is reported here. the histopathologic report confirmed the diagnosis. pleomorphic adenoma is most common in salivary glands but very rare in sweat glands. pleomorphic adenoma in sweat gland and the similar tumors of eccring sweat gland are described that bear a striking resemblance to pleomorphic adenomas of salivary gland. upon closer examination, t...

Eccrine sweat glands, which are distributed over the whole bodies of primates and humans, have long been regarded mainly to have a function in thermoregulation. However, the discovery of dermcidin-derived antimicrobial peptides in eccrine sweat demonstrated that sweat actively participates in the constitutive innate immune defense of human skin against infection. In the meantime, a number of st...

Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Both lesions had no clear distinctive features, enhancing the need of high-level...

Figure 1. Intraoperative view of left foot showing the tumor on the third toe (top left). Low-powered view of mass showing well-circumscribed tumor and pseudoencapsulation (top right). Medium-powered view of mass showing bland morphology of cells and mucinous features (bottom left). High-powered view of mass showing bland morphology and mucinous features (bottom right). DESCRIPTION A 26-year-ol...