Viral haemorrhagic fevers (VHFs) are currently at the forefront of the world's attention due to the recent Zaire ebola virus epidemic in West Africa. This epidemic has highlighted the frailty of the world's public health response mechanisms and demonstrated the potential risks to nations around the world of imported cases of epidemic diseases. While imported cases in children are less likely, t...

The Ebola Hemorrhagic Fever, caused by the virus, is a rare but severe disease and claims fatality rate of 50%. Although its origins date back to 1970s, epidemic in 2014-2016 marked most prominent appearance.

1. World Health Organization. Eighth Meeting of the WHO Advisory Group on the EVD Response; 2015 Mar 20; Geneva. Geneva: The Organization; 2015 [cited 2015 Mar 25]. http://www.who.int/ csr/disease/ebola/advisory-groups/8th-meeting-report.pdf?ua=1 2. World Health Organization. WHO Statement on the Meeting of the International Health Regulations Emergency Committee Regarding the 2014 Ebola Outbre...

Ebola hemorrhagic fever is a fatal disease caused by the negative-strand RNA of the Ebola virus. A high-intensity outbreak of this fever was reported in West Africa last year; however, there is currently no definitive treatment strategy available for this disease. In this study, we analyzed the molecular evolutionary history and attempted to determine the positive selection sites in the Ebola g...

Ebola hemorrhagic fever is a deadly disease caused by several species of ebolavirus. The current outbreak of 2014 is unique in that it has affected a greater number of people than ever before. It also has an unusual geographic distribution. Nonspecific findings such as fever and generalized weakness have traditionally been very common early in the acute phase. Ophthalmic manifestations have als...

Two large outbreaks of Ebola hemorrhagic fever occurred in Uganda in 2000 and 2007. In May 2011, we identified a single case of Sudan Ebola virus disease in Luwero District. The establishment of a permanent in-country laboratory and cooperation between international public health entities facilitated rapid outbreak response and control activities.

Infections among health care workers have played a major role in outbreaks of Ebola virus disease since the virus was discovered in 1976. Available data from past outbreaks show that the deaths of health care workers were the canary in the coal mine signaling that an outbreak of a viral hem­ orrhagic fever had begun. The current Ebola outbreak that is devastating West Africa is unfortunately no...

media coverage when outbreaks occur. The causative organisms are found in tropical Africa and the Philippines. They belong to the Filoviridae family. Clinical presentations of the viral infections they cause share many common characteristics. At least 6 Marburg virus outbreaks and 21 Ebola virus outbreaks have been documented to date (Table 1). More outbreaks have probably occurred in remote ar...