What is hunger? How do we know how much to eat? And what happens if not eat enough? To survive, the human body must have energy reserves available in form of fat. Using a hormone called leptin, fat tissue regularly sends messages brain about body’s reserves. When receives lot it tells body, “you are full, stop eating.” In certain situations, like obesity and pregnancy, less sensitive leptin—so ...

BACKGROUND AND OBJECTIVE Epicardial adipose tissue (EAT) volume is associated with coronary plaque burden and adverse events. We aimed to determine, whether CT-derived EAT attenuation in addition to EAT volume distinguishes patients with and without myocardial infarction. METHODS AND RESULTS In 94 patients with confirmed or suspected coronary artery disease (aged 66.9±14.7years, 61%male) unde...

Introduction: Consumption of fresh herbs plays a major epidemiological role in the transmission of some parasitic food-borne diseases. Some manufacturers are producing different kinds of fresh packaged ready-to-eat packaged herbs in Iran. Therefore, this study was carried out in order to evaluate the parasitic contamination in ready-to-eat fresh packaged herbs produced by one of major manufactu...

The C. elegans eat-6 gene encodes a Na(+), K(+)-ATPase alpha subunit and is a homolog of the familial hemiplegic migraine candidate gene FHM2. Migraine is the most common neurological disorder linked to serotonergic dysfunction. We sought to study the pathophysiological mechanisms of migraine and their relation to serotonin (5-HT) signaling using C. elegans as a genetic model. In C. elegans, ex...

Introduction. Adipose tissue is the largest endocrine organ, composed of subcutaneous (SAT) and visceral adipose tissue (VAT), the latter being highly associated with coronary artery disease (CAD). Expansion of epicardial adipose tissue (EAT) is linked to CAD. One way of assessing the CAD risk is with low-cost anthropometric measures, although they are inaccurate and cannot discriminate between...

Epicardial adipose tissue (EAT) has been found to be an important reliable marker for future coronary events. Deposition of the EAT in young individuals is not well known. We studied EAT in 25 young overweight or obese individuals. In spite of the high visceral fat and total body fat, EAT thickness was not found to be high in the participants of our study.