PURPOSE This study aimed to evaluate the clinicopathological characteristics of pregnancy-associated breast cancer (PABC) in comparison with non-pregnancy associated breast cancer (non-PABC). METHODS A total of 344 eligible patients with PABC were identified in the Korean Breast Cancer Society Registry database. PABC was defined as ductal carcinoma in situ, invasive ductal carcinoma, or invas...

The etiological role of genotype and environment in recalled age at menarche was examined using an unselected sample of 1,177 MZ and 711 DZ twin pairs aged 18 years and older. The correlation for onset of menarche between MZ twins was .65 +/- .03, and that for DZ pairs was .18 +/- .04, although these differed somewhat between four birth cohorts. Environmental factors were more important in the ...

We examined associations of age at menarche and menstrual characteristics with the risk of preeclampsia among participants (n = 3,365) of a pregnancy cohort study. Data were collected using in-person interviews and medical record abstraction. Logistic regression was used to estimate adjusted odds ratio (OR) and 95% confidence interval (95% CI). There was a significant inverse association betwee...

Prior research indicates that being reared in a stressful environments is associated with earlier onset of menarche in girls. In this research, we examined (a) whether these effects are driven by exposure to certain dimensions of stress (harshness or unpredictability) during the first 5 years of life, and (b) whether the negative effects of stress on the timing of menarche are buffered by secur...

STUDY QUESTION Is sugar-sweetened beverage (SSB) consumption associated with age at menarche? SUMMARY ANSWER More frequent SSB consumption was associated with earlier menarche in a population of US girls. WHAT IS KNOWN ALREADY SSB consumption is associated with metabolic changes that could potentially impact menarcheal timing, but direct associations with age at menarche have yet to be inve...

Background: The age of maternal menarche is thought to be intergenerationally associated with the incidence overweight and obesity in their offspring, but studies are limited. Objective: To determine intergenerational relationship between at childhood preschool age. Methods: This research an analytic cross-sectional study a cluster sampling method which was conducted Denpasar, Bali. Younger def...

Long-standing untreated primary hypothyroidism is an uncommon cause of praecocious puberty. The hypothyroidism, incomplete sexual maturation, galactorrhoea, and pituitary enlargement are reversed or corrected by levothyroxine therapy within a few months. We report a young girl with juvenile hypothyroidism who presented with early onset of menarche with failure of growth who was treated successf...