BACKGROUND Current antidepressants are clinically effective only after several weeks of administration. Tetramethylpyrazine (TMP) is an identified component of Ligusticum wallichii with neuroprotective effects. Here, we investigated the antidepressant effects of TMP in mice models of depression. METHODS Antidepressant effects of TMP were first detected in the forced swim test (FST) and tail s...

To the Editor: Coronary revascularization has been well-established as the most effective treatment of limiting the eventual infarct size for coronary artery diseases. However, reperfusion can elicit a number of adverse reactions that may limit its beneficial actions. Although reduction of ischemia reperfusion (IR) injury through the use of antioxidant therapy, calcium-channel blockers, sodium-...

The aim of this study was to evaluate the natural regeneration status tree flora at Bangabandhu Sheikh Mujib Safari Park (BSMSP) in Dulahazara, Cox’s Bazar. Six blocks were created within safari park explore potential. A total 41 sample plots 5m × size, each centered middle a 20m vegetation survey plot, taken. In total, 835 seedlings representing 56 species under 29 families recorded. Euphorbia...