The role of symbiosis in macro-evolution is poorly understood. On the one hand, symbiosis seems to be a perfectly normal manifestation of individual selection, on the other hand, in some of the major transitions in evolution it seems to be implicated in the creation of new higher-level units of selection. Here we present a model of individual selection for symbiotic relationships where individu...

Maintenance of recombinant plasmid vectors in host bacteria relies on the presence of selection antibiotics in the growth media to suppress plasmid -free segregants. However, presence of antibiotic resistance genes and antibiotics themselves is not acceptable in several applications of biotechnology. Previously, we have shown that FabV-Triclosan selection system can be used to select high and m...

We model parental sex selection and the equilibrium sex ratio. With intrinsic son preference, sex selection results in a male-biased sex ratio. This is ine¢ cient, due to a marriage market congestion externality. Medical innovations that facilitate selection increase ine¢ ciency. If son preference arises endogenously, due to population growth causing an excess of women on the marriage market, s...

Despite its grounding in creativity techniques, merging multiple source sketches to create new ideas has received scant attention in design literature. In this paper, we identify the physical operations that in merging sketch components. We also introduce cognitive operations of reuse, repurpose, refactor, and reinterpret, and explore their relevance to creative design. To examine the relations...

The advent of next generation sequencing technologies has made whole-genome and whole-population sampling possible, even for eukaryotes with large genomes. With this development, experimental evolution studies can be designed to observe molecular evolution "in action" via evolve-and-resequence (E&R) experiments. Among other applications, E&R studies can be used to locate the genes and variants ...

Reproductive character displacement occurs when sympatric and allopatric populations of a species differ in traits crucial to reproduction, and it is commonly thought of as a signal of selection acting to limit hybridization. Most documented cases of reproductive character displacement involve characters that are poorly understood at the genetic level, and rejecting alternative hypotheses for b...

An alloantigen is a genetically determined cell-surface molecule detected by specific antisera. An identifying letter has been assigned to each genetic locus responsible for the 12 distinct families of alloantigens: A, B, C, D, E, H, I, J, K, L, P, and R. The genes of each system segregate independently of the other systems, except that the A and E are very closely linked (0.5 centimorgans). Se...

replacement of a tractor is an influential factor affecting timely farm operation. the accurate prediction of repair and maintenance costs is essential to selection of a replacement model. this study used empirical data for 60 two-wheel drive (2wd) tractors from astan ghods-e razavi agroindustry. the types and numbers of tractors used were the massey ferguson 285 (17), fiat (10), john deere 314...

Selection has been invaluable for genetic manipulation, although counter-selection has historically exhibited limited robustness and convenience. TolC, an outer membrane pore involved in transmembrane transport in E. coli, has been implemented as a selectable/counter-selectable marker, but counter-selection escape frequency using colicin E1 precludes using tolC for inefficient genetic manipulat...

The selective mechanisms for maintaining polymorphism in natural populations has been the subject of theory, experiments, and review over the past half century. Advances in molecular genetic techniques have provided new insight into many examples of balancing selection. In addition, new theoretical developments demonstrate how diversifying selection over environments may maintain polymorphism. ...