Léčba dyslipidemie představuje velmi dynamicky rostoucí segment farmakoterapie včetně výroby biologických prostředků. Ty dnes cíleně míří na různé proteiny, které se podílejí syntéze, transportu nebo metabolismu lipoproteinů. Sdělení podává přehled o současných možnostech biologické léčby dyslipidemií a léčivých prostředcích, mají potenciál rozšířit j...

Dyslipidemia is a primary driver for chronic cardiovascular conditions and there is no comprehensive literature about its management in South Africa. The objective of this study was to assess the prevalence, awareness, treatment, and control of dyslipidemia in rural South Africa and how they are impacted by different behaviors and non-modifiable factors. To fulfill this objective we recruited f...

We have previously shown that the C→T polymorphism (rs6929846) of the butyrophilin, subfamily 2, member A1 gene (BTN2A1) was significantly associated with myocardial infarction. Considering that dyslipidemia is a significant risk factor for coronary heart disease, it was hypothesized that the association between rs6929846 of BTN2A1 and myocardial infarction may be attributable, at least in part...

487 In 1836, Richard Bright commented on the “mil­ ky serum” of patients with (what today would be called) end­stage renal disease (ESRD) – almost certainly the first recognition of hyper­ lipidemia. The relation between heavy proteinu­ ria with dyslipidemia had been noted at the be­ ginning of the 20th century and indeed dyslip­ idemia in patients with nephrotic proteinuria differs in many res...

BACKGROUND/OBJECTIVES Recently, a body shape index (ABSI) was reported to predict all-cause mortality independently of body mass index (BMI) in Americans. This study aimed to evaluate whether ABSI is applicable to Japanese adults as a predictor for development of diabetes, hypertension, and dyslipidemia. SUBJECTS/METHODS We evaluated the predictive power of ABSI in a retrospective cohort stud...

Dyslipidemia in cancer patients is reported to be linked with cancer risk and progression of the disease. Previous research findings showed that low levels of serum cholesterol and elevated levels of serum triglycerides are associated with risk of overall cancers. However, there are several inconsistencies in the reports regarding the association of dyslipidemia with cancers. In this book chapt...